6M7V
Human DNA polymerase eta extension complex with cdA at the -1 position
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (P) | DNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3') | polymer | 8 | 2497.7 | 1 | Homo sapiens | ||
| 3 | C (T) | DNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3') | polymer | 9 | 2657.8 | 1 | Homo sapiens | ||
| 4 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | E (A) | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine | non-polymer | 490.2 | 1 | Chemie (DZ4) | |||
| 6 | F, G (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 7 | H, I, J (A, P, T) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53773.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 658.8 | |
| All* | Total formula weight | 54431.9 |
