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6M7V

Human DNA polymerase eta extension complex with cdA at the -1 position

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2PDNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3')polymer82497.71Homo sapiens
3TDNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3')polymer92657.81Homo sapiens
4ANICKEL (II) IONnon-polymer58.71Chemie (NI)
5A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosinenon-polymer490.21Chemie (DZ4)
6AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
7waterwater18.017Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight53773.1
Non-Polymers*Number of molecules4
Total formula weight658.8
All*Total formula weight54431.9
*Water molecules are not included.

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PDB entries from 2024-05-01

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