6M7V

Human DNA polymerase eta extension complex with cdA at the -1 position

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NI A 501

Chain	Residue
A	ASP181
A	HIS289
A	HIS393
A	HIS397

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site_id	AC2
Number of Residues	15
Details	binding site for residue DZ4 A 502

Chain	Residue
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ASP115
A	MN503
A	MN504
A	HOH606
P	DT9
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MN A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	DZ4502
A	MN504

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MN A 504

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	DZ4502
A	MN503
A	HOH606
P	DT9

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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