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6M7V

Human DNA polymerase eta extension complex with cdA at the -1 position

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue NI A 501
ChainResidue
AASP181
AHIS289
AHIS393
AHIS397

site_idAC2
Number of Residues15
Detailsbinding site for residue DZ4 A 502
ChainResidue
APHE18
AILE48
AALA49
ATYR52
AARG55
AASP115
AMN503
AMN504
AHOH606
PDT9
AASP13
AMET14
AASP15
ACYS16
APHE17

site_idAC3
Number of Residues5
Detailsbinding site for residue MN A 503
ChainResidue
AASP13
AMET14
AASP115
ADZ4502
AMN504

site_idAC4
Number of Residues7
Detailsbinding site for residue MN A 504
ChainResidue
AASP13
AASP115
AGLU116
ADZ4502
AMN503
AHOH606
PDT9

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

226707

PDB entries from 2024-10-30

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