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PDB: 12920 件

2ASQ
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Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM)
分子名称: Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1
著者Song, J, Zhang, Z, Hu, W, Chen, Y.
登録日2005-08-23
公開日2005-10-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation
J.Biol.Chem., 280, 2005
5E1D
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NTMT1 in complex with YPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1O
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Crystal structure of NTMT1 in complex with RPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E26
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Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者DONG, A, LOPPNAU, P, RAVICHANDRAN, M, CHENG, C, TEMPEL, W, SEITOVA, A, HUTCHINSON, A, HONG, B.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, Structural Genomics Consortium (SGC)
登録日2015-09-30
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
to be published
2FC7
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Solution structure of the ZZ domain of ZZZ3 protein
分子名称: ZINC ION, ZZZ3 protein
著者Dang, W, Muto, Y, Inoue, M, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-12
公開日2006-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the ZZ domain of ZZZ3 protein
To be published
2FDO
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Crystal Structure of the Conserved Protein of Unknown Function AF2331 from Archaeoglobus fulgidus DSM 4304 Reveals a New Type of Alpha/Beta Fold
分子名称: Hypothetical protein AF2331
著者Wang, S, Kirillova, O, Chruszcz, M, Cymborowski, M.T, Skarina, T, Gorodichtchenskaia, E, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2005-12-14
公開日2006-01-31
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.
Protein Sci., 18, 2009
4CCJ
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60S ribosomal protein L8 histidine hydroxylase (NO66) in apo form
分子名称: 1,2-ETHANEDIOL, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66
著者Chowdhury, R, Ge, W, Clifton, I.J, Schofield, C.J.
登録日2013-10-23
公開日2014-05-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
5ELZ
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Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N-(1,3-benzodioxol-5-ylmethyl)-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ...
著者Mottaghi, K, Hughes, S.J, Tempel, W, Hong, B, Park, H, Structural Genomics Consortium (SGC)
登録日2015-11-05
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product.
Acs Infect Dis., 2, 2016
2FI9
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The crystal structure of an outer membrane protein from the Bartonella henselae
分子名称: Outer membrane protein
著者Zhang, R, Hatzos, C, Clancy, S, Collart, F, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-12-28
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8A crystal structure of an outer membrane protein from the Bartonella henselae
To be Published
2C6G
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Membrane-bound glutamate carboxypeptidase II (GCPII) with bound glutamate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Mesters, J.R, Barinka, C, Li, W, Tsukamoto, T, Majer, P, Slusher, B.S, Konvalinka, J, Hilgenfeld, R.
登録日2005-11-09
公開日2006-02-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer.
EMBO J., 25, 2006
3DCA
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Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target
分子名称: RPA0582, SULFATE ION
著者Sledz, P, Wang, S, Chruszcz, M, Yim, V, Kudritska, M, Evdokimova, E, Turk, D, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2008-06-03
公開日2008-08-05
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target
To be Published
2F89
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Crystal structure of human FPPS in complex with pamidronate
分子名称: Farnesyl Diphosphate Synthase, MANGANESE (II) ION, PAMIDRONATE, ...
著者Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
登録日2005-12-02
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
4NIZ
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GCN4-p1 single Val9 to aminobutyric acid mutant
分子名称: GLYCEROL, General control protein GCN4
著者Oshaben, K.M, Horne, W.S.
登録日2013-11-08
公開日2014-08-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity.
Biomacromolecules, 15, 2014
4NJ2
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GCN4-p1 triple Val9, 23,30 to Ile mutant
分子名称: GLYCEROL, General control protein GCN4
著者Oshaben, K.M, Horne, W.S.
登録日2013-11-08
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity.
Biomacromolecules, 15, 2014
2F94
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Crystal structure of human FPPS in complex with ibandronate
分子名称: Farnesyl Diphosphate Synthase, IBANDRONATE, PHOSPHATE ION, ...
著者Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
登録日2005-12-05
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
7VQ1
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Structure of Apo-hsTRPM2 channel
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W.
登録日2021-10-18
公開日2021-12-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
7VQ2
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Structure of Apo-hsTRPM2 channel TM domain
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W.
登録日2021-10-18
公開日2021-12-22
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
2FC9
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Solution structure of the RRM_1 domain of NCL protein
分子名称: NCL protein
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-12
公開日2006-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the RRM_1 domain of NCL protein
To be published
2BPR
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NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES
分子名称: DNAK
著者Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P.
登録日1998-08-11
公開日1999-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.
Biochemistry, 37, 1998
2FHX
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Pseudomonas aeruginosa SPM-1 metallo-beta-lactamase
分子名称: 1,2-ETHANEDIOL, AZIDE ION, CHLORIDE ION, ...
著者Murphy, T.A, Catto, L.E, Halford, S.E, Hadfield, A.T, Minor, W, Walsh, T.R, Spencer, J.
登録日2005-12-27
公開日2006-01-17
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Pseudomonas aeruginosa SPM-1 Provides Insights into Variable Zinc Affinity of Metallo-beta-lactamases.
J.Mol.Biol., 357, 2006
3D94
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Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP
分子名称: 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine, CALCIUM ION, Insulin-like growth factor 1 receptor beta chain
著者Wu, J, Li, W, Miller, W.T, Hubbard, S.R.
登録日2008-05-26
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor
Embo J., 27, 2008
5EMG
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Crystal structures of PNA p(GCTGCTGC)2 duplex containing T-T mismatches
分子名称: CHLORIDE ION, GPN-CPN-TPN-GPN-CPN-TPN-GPN-CPN, SODIUM ION
著者Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W.
登録日2015-11-06
公開日2016-01-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.
Nucleic Acids Res., 44, 2016
3DSS
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Crystal structure of RabGGTase(DELTA LRR; DELTA IG)
分子名称: CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ...
著者Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
登録日2008-07-14
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
2FBM
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Acetyltransferase domain of CDY1
分子名称: CHLORIDE ION, Y chromosome chromodomain protein 1, telomeric isoform b
著者Min, J.R, Antoshenko, T, Hong, W, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-12-09
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal Structure of Acetyltransferases domain of Human Testis-specific chromodomain protein Y 1
To be Published
2C4E
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Crystal Structure of Methanocaldococcus jannaschii Nucleoside Kinase - An Archaeal Member of the Ribokinase Family
分子名称: MAGNESIUM ION, SUGAR KINASE MJ0406
著者Arnfors, L, Hansen, T, Meining, W, Schoenheit, P, Ladenstein, R.
登録日2005-10-18
公開日2006-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of Methanocaldococcus Jannaschii Nucleoside Kinase: An Archaeal Member of the Ribokinase Family.
Acta Crystallogr.,Sect.D, 62, 2006

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