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PDB: 1180 results

8BW4
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BU of 8bw4 by Molmil
PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Descriptor: (2R)-4-(3-fluoranylthiophen-2-yl)carbonyl-N-(4-methoxyphenyl)-2-methyl-piperazine-1-carboxamide, PH-interacting protein
Authors:Grosjean, H, Aimon, A, Hassell-Hart, S, Bradshaw, W.J, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Biggin, P.C, Spencer, J, von Delft, F.
Deposit date:2022-12-06
Release date:2022-12-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
To Be Published
8BW2
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BU of 8bw2 by Molmil
PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Descriptor: (2R)-N-(2-methoxyethyl)-2-methyl-4-thiophen-2-ylcarbonyl-piperazine-1-carboxamide, PH-interacting protein
Authors:Grosjean, H, Aimon, A, Hassell-Hart, S, Bradshaw, W.J, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Biggin, P.C, Spencer, J, von Delft, F.
Deposit date:2022-12-06
Release date:2022-12-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
To Be Published
8BLV
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BU of 8blv by Molmil
The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Syndecan-4, ...
Authors:Bradshaw, W.J, Katis, V.L, Daniel-Mozo, M, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2022-11-10
Release date:2022-12-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide
To Be Published
2CNP
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BU of 2cnp by Molmil
HIGH RESOLUTION SOLUTION STRUCTURE OF APO RABBIT CALCYCLIN, NMR, 22 STRUCTURES
Descriptor: CALCYCLIN
Authors:Maler, L, Potts, B.C.M, Chazin, W.J.
Deposit date:1999-01-07
Release date:1999-07-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High resolution solution structure of apo calcyclin and structural variations in the S100 family of calcium-binding proteins.
J.Biomol.NMR, 13, 1999
2SAS
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BU of 2sas by Molmil
STRUCTURE OF A SARCOPLASMIC CALCIUM-BINDING PROTEIN FROM AMPHIOXUS REFINED AT 2.4 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SARCOPLASMIC CALCIUM-BINDING PROTEIN
Authors:Cook, W.J, Babu, Y.S, Cox, J.A.
Deposit date:1993-07-30
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a sarcoplasmic calcium-binding protein from amphioxus refined at 2.4 A resolution.
J.Mol.Biol., 229, 1993
2TPT
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BU of 2tpt by Molmil
STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE
Descriptor: SULFATE ION, THYMIDINE PHOSPHORYLASE
Authors:Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E.
Deposit date:1997-11-24
Release date:1999-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
6XY7
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BU of 6xy7 by Molmil
Human SHIP1 with magnesium and phosphate bound to the active site
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Bradshaw, W.J, Scacioc, A, Fernandez-Cid, A, Mckinley, G, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O.
Deposit date:2020-01-29
Release date:2020-02-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.086 Å)
Cite:Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
Structure, 2024
6XQ6
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BU of 6xq6 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 11
Descriptor: 3-phenoxyphenol, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ3
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BU of 6xq3 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 3-(3-{[3-(4-carboxyphenoxy)phenyl]methoxy}phenyl)-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ8
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BU of 6xq8 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 11
Descriptor: 3-phenoxyphenol, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ5
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BU of 6xq5 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 1
Descriptor: 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ7
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BU of 6xq7 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 5
Descriptor: 5-bromo-3-methyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ9
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BU of 6xq9 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 13
Descriptor: 4-(3-hydroxyphenoxy)benzoic acid, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ1
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BU of 6xq1 by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 3-[3-({[3-(4-carboxyphenoxy)phenyl]methoxy}methyl)phenyl]-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
1UBQ
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BU of 1ubq by Molmil
STRUCTURE OF UBIQUITIN REFINED AT 1.8 ANGSTROMS RESOLUTION
Descriptor: UBIQUITIN
Authors:Vijay-Kumar, S, Bugg, C.E, Cook, W.J.
Deposit date:1987-01-02
Release date:1987-04-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of ubiquitin refined at 1.8 A resolution.
J.Mol.Biol., 194, 1987
3PMG
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BU of 3pmg by Molmil
STRUCTURE OF RABBIT MUSCLE PHOSPHOGLUCOMUTASE AT 2.4 ANGSTROMS RESOLUTION. USE OF FREEZING POINT DEPRESSANT AND REDUCED TEMPERATURE TO ENHANCE DIFFRACTIVITY
Descriptor: MAGNESIUM ION, Phosphoglucomutase-1
Authors:Ray Junior, W.J, Liu, Y, Baranidharan, S.
Deposit date:1995-03-02
Release date:1995-12-07
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.
Acta Crystallogr.,Sect.D, 53, 1997
6RRP
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BU of 6rrp by Molmil
Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper and phenylthiourea
Descriptor: COPPER (II) ION, N-PHENYLTHIOUREA, PvdP
Authors:Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J.
Deposit date:2019-05-20
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa.
Int.J.Biol.Macromol., 146, 2020
1FVT
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BU of 1fvt by Molmil
THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR
Descriptor: 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2
Authors:Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K.
Deposit date:2000-09-20
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
1FVV
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THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR
Descriptor: 4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
Authors:Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K.
Deposit date:2000-09-20
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
7TL3
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BU of 7tl3 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.066 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL2
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BU of 7tl2 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL4
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BU of 7tl4 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
6TXS
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BU of 6txs by Molmil
The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide
Descriptor: CD44 antigen, Moesin
Authors:Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2020-01-14
Release date:2020-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
6TXQ
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BU of 6txq by Molmil
The high resolution structure of the FERM domain and helical linker of human moesin
Descriptor: ACETATE ION, Moesin
Authors:Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2020-01-14
Release date:2020-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
2BCB
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BU of 2bcb by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K
Descriptor: CALBINDIN D9K
Authors:Kordel, J, Skelton, N.J, Akke, M, Chazin, W.J.
Deposit date:1993-08-18
Release date:1993-10-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High-resolution structure of calcium-loaded calbindin D9k.
J.Mol.Biol., 231, 1993

221051

数据于2024-06-12公开中

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