4UEL

UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain

Summary for 4UEL

Related4UEM
DescriptorUBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, POLYUBIQUITIN-B, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1, ... (4 entities in total)
Functional Keywordshydrolase, deubiquitinating enzyme, dub, uch37, uchl5, proteasome, adrm1, rpn13, deubad, uch, ubiquitin-propargyl
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains3
Total molecular weight59359.47
Authors
Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K. (deposition date: 2014-12-18, release date: 2015-03-04, Last modification date: 2019-04-03)
Primary citation
Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K.
Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57:887-, 2015
PubMed: 25702870 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2014.12.039
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23810 0.7% 3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report