4UEL

UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5	polymer	331	37734.9	1	UniProt (Q9Y5K5) Pfam (PF01088) Pfam (PF18031)	HOMO SAPIENS (HUMAN)	UCH-L5, UBIQUITIN C-TERMINAL HYDROLASE UCH37, UBIQUITIN THIOESTERASE L5
2	B (B)	POLYUBIQUITIN-B	polymer	76	8558.9	1	UniProt (P0CG47) Pfam (PF00240)	HOMO SAPIENS	UBIQUITIN
3	C (C)	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1	polymer	127	13065.7	1	UniProt (Q16186) Pfam (PF16550)	HOMO SAPIENS (HUMAN)	RPN13,110 KDA CELL MEMBRANE GLYCOPROTEIN, GP110, ADHESION-REGULATING MOLECULE 1, ARM-1, PROTEASOME REGULATORY PARTICLE NON-ATPASE 13, HRPN13, RPN13 HOMOLOG
4	D, E, F (A, B, C)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A: 1 - 328 (UniProt: Q9Y5K5)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

B: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Aye 76	Gly 76	engineered mutation

C: 266 - 388 (UniProt: Q16186)

PDB	External Database	Details
Gly 262	-	expression tag
Pro 263	-	expression tag
Gly 264	-	expression tag
Ser 265	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	59359.5
All*	Total formula weight	59359.5

*Water molecules are not included.