4UF6

UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G

Summary for 4UF6

Entry DOI	10.2210/pdb4uf6/pdb
Descriptor	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5, POLYUBIQUITIN-B, NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN (3 entities in total)
Functional Keywords	hydrolase, deubiquitinating enzyme
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	12
Total formula weight	215071.43
Authors	Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K. (deposition date: 2014-12-23, release date: 2015-03-04, Last modification date: 2019-04-03)
Primary citation	Sahtoe, D.D.,Van Dijk, W.J.,El Oualid, F.,Ekkebus, R.,Ovaa, H.,Sixma, T.K. Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G. Mol.Cell, 57:887-, 2015 Cited by PubMed: 25702870 DOI: 10.1016/J.MOLCEL.2014.12.039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.69 Å)

Structure validation