5ZC9
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![BU of 5zc9 by Molmil](/molmil-images/mine/5zc9) | Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex | 分子名称: | (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | 著者 | Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. | 登録日 | 2018-02-16 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Mol. Cell, 73, 2019
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5Z1Q
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![BU of 5z1q by Molmil](/molmil-images/mine/5z1q) | Crystal structures of the trimeric N-terminal domain of Ciliate Euplotes octocarinatus Centrin | 分子名称: | CALCIUM ION, CHLORIDE ION, Centrin protein | 著者 | Wang, W, Zhao, Y, Yang, B, Wang, H. | 登録日 | 2017-12-27 | 公開日 | 2018-04-25 | 最終更新日 | 2018-06-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions Protein Sci., 27, 2018
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5Z9Y
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![BU of 5z9y by Molmil](/molmil-images/mine/5z9y) | Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | 著者 | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | 登録日 | 2018-02-05 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497, 2018
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5Z6B
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![BU of 5z6b by Molmil](/molmil-images/mine/5z6b) | Crystal structure of sugar-binding protein YesO in complex with rhamnogalacturonan trisaccharide | 分子名称: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-2)-[beta-D-galactopyranose-(1-4)]alpha-L-rhamnopyranose, Putative ABC transporter substrate-binding protein YesO | 著者 | Sugiura, H, Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | 登録日 | 2018-01-22 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.582 Å) | 主引用文献 | Crystal structure of sugar-binding protein YesO in complex with rhamnogalacturonan trisaccharide To Be Published
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5ZHK
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![BU of 5zhk by Molmil](/molmil-images/mine/5zhk) | Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor | 分子名称: | N-[(4-{[cyclohexyl(ethyl)amino]methyl}phenyl)methyl]-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. | 登録日 | 2018-03-13 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. J.Med.Chem., 62, 2019
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5WRG
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![BU of 5wrg by Molmil](/molmil-images/mine/5wrg) | SARS-CoV spike glycoprotein | 分子名称: | Spike glycoprotein | 著者 | Gui, M, Song, W, Xiang, Y, Wang, X. | 登録日 | 2016-12-01 | 公開日 | 2017-01-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding. Cell Res., 27, 2017
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5WSA
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![BU of 5wsa by Molmil](/molmil-images/mine/5wsa) | Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate and allosteric activator Glucose 6-Phosphate | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, OXALATE ION, ... | 著者 | Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. | 登録日 | 2016-12-06 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8, 2017
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5WPX
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5WHS
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![BU of 5whs by Molmil](/molmil-images/mine/5whs) | Crystal structure of the catalase-peroxidase from Neurospora crassa at 2.6 A | 分子名称: | Catalase-peroxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Diaz-Vilchis, A, Vega-Garcia, V, Rudino-Pinera, E, Hansberg, W. | 登録日 | 2017-07-18 | 公開日 | 2018-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase. Arch. Biochem. Biophys., 640, 2018
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5W1E
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![BU of 5w1e by Molmil](/molmil-images/mine/5w1e) | PobR in complex with PHB | 分子名称: | GLYCEROL, P-HYDROXYBENZOIC ACID, Putative transcriptional regulator, ... | 著者 | Page, R, Peti, W, Lord, D.M, Bajaj, R, Zhang, R. | 登録日 | 2017-06-02 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | A peculiar IclR family transcription factor regulates para-hydroxybenzoate catabolism in Streptomyces coelicolor. Nucleic Acids Res., 46, 2018
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5W1J
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5VNJ
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7FDZ
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![BU of 7fdz by Molmil](/molmil-images/mine/7fdz) | Levansucrase from Brenneria sp. EniD 312 with sucrose | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Xu, W, Hou, X.D, Rao, Y.J, Pijning, T, Guskov, A, Mu, W.M. | 登録日 | 2021-07-19 | 公開日 | 2022-04-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity. J.Agric.Food Chem., 70, 2022
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5ZO1
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![BU of 5zo1 by Molmil](/molmil-images/mine/5zo1) | Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain (Ig1-Ig3), 2.2A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 4, GLYCEROL | 著者 | Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X. | 登録日 | 2018-04-12 | 公開日 | 2019-01-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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7F3B
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![BU of 7f3b by Molmil](/molmil-images/mine/7f3b) | cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor. | 分子名称: | 7-[(2-fluorophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, GLYCEROL | 著者 | Wang, H, You, X.F, Yang, X.Y, Li, Y, Hong, W. | 登録日 | 2021-06-16 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur.J.Med.Chem., 228, 2022
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5ZBR
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![BU of 5zbr by Molmil](/molmil-images/mine/5zbr) | Crystal Structure of Kinesin-3 KIF13B motor domain in AMPPNP form | 分子名称: | Kinesin family member 13B, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Ren, J.Q, Wang, S, Feng, W. | 登録日 | 2018-02-12 | 公開日 | 2018-05-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement. J. Mol. Biol., 430, 2018
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5WBV
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![BU of 5wbv by Molmil](/molmil-images/mine/5wbv) | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor | 分子名称: | 2-chloro-5-(4-methyl-6-oxo-3-phenylpyrano[2,3-c]pyrazol-1(6H)-yl)benzoic acid, Histone-lysine N-methyltransferase KMT5B, S-ADENOSYLMETHIONINE, ... | 著者 | Halabelian, L, Tempel, W, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2017-06-29 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor To be published
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7CKF
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5WHQ
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![BU of 5whq by Molmil](/molmil-images/mine/5whq) | Crystal structure of the catalase-peroxidase from Neurospora crassa at 2.9 A | 分子名称: | Catalase-peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Diaz-Vilchis, A, Vega-Garcia, V, Rudino-Pinera, E, Hansberg, W. | 登録日 | 2017-07-18 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase. Arch. Biochem. Biophys., 640, 2018
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5W96
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![BU of 5w96 by Molmil](/molmil-images/mine/5w96) | Solution structure of phage derived peptide inhibitor of frizzled 7 receptor | 分子名称: | Fz7 binding peptide | 著者 | Nile, A.H, de Sousa e Melo, F, Mukund, S, Piskol, R, Hansen, S, Zhou, L, Zhang, Y, Fu, Y, Gogol, E.B, Komuves, L.G, Modrusan, Z, Angers, S, Franke, Y, Koth, C, Fairbrother, W.J, Wang, W, de Sauvage, F.J, Hannoush, R.N. | 登録日 | 2017-06-22 | 公開日 | 2018-04-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat. Chem. Biol., 14, 2018
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5WPY
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5W0S
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![BU of 5w0s by Molmil](/molmil-images/mine/5w0s) | GroEL using cryoEM | 分子名称: | 60 kDa chaperonin | 著者 | Roh, S.H, Chiu, W. | 登録日 | 2017-05-31 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5W5G
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![BU of 5w5g by Molmil](/molmil-images/mine/5w5g) | Structure of Human Sts-1 histidine phosphatase domain | 分子名称: | Ubiquitin-associated and SH3 domain-containing protein B | 著者 | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | 登録日 | 2017-06-15 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2. Biochemistry, 56, 2017
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7EXC
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![BU of 7exc by Molmil](/molmil-images/mine/7exc) | Crystal structure of T2R-TTL-1129A2 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | 著者 | Yang, J.H, Yan, W. | 登録日 | 2021-05-26 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure-Based Design and Synthesis of N-Substituted 3-Amino-beta-Carboline Derivatives as Potent alpha beta-Tubulin Degradation Agents J.Med.Chem., 65, 2022
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5VZX
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![BU of 5vzx by Molmil](/molmil-images/mine/5vzx) | Crystal structure of crenezumab Fab | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Crenezumab Fab heavy chain, ... | 著者 | Ultsch, M, Wang, W. | 登録日 | 2017-05-29 | 公開日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin. Sci Rep, 6, 2016
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