5WS9
 
 | | Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, ATP and allosteric activator AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. | | 登録日 | 2016-12-06 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nat Commun, 8, 2017
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5WTZ
 | | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NAD+ | | 分子名称: | Binary enterotoxin of Clostridium perfringens component a, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | | 登録日 | 2016-12-15 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin
PLoS ONE, 12, 2017
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5WUV
 | | Crystal structure of Certolizumab Fab | | 分子名称: | heavy chain, light chain | | 著者 | Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y. | | 登録日 | 2016-12-21 | | 公開日 | 2017-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Int J Mol Sci, 18, 2017
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5WZ1
 | | Crystal structure of Zika virus NS5 methyltransferase bound to S-adenosyl-L-methionine | | 分子名称: | NS5 methyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | | 登録日 | 2017-01-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.507 Å) | | 主引用文献 | The crystal structure of Zika virus NS5 reveals conserved drug targets.
EMBO J., 36, 2017
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5X0R
 | | Crystal Structure of PXR LBD Complexed with SJB7 | | 分子名称: | 4-[(4-tert-butylphenyl)sulfonyl]-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole, Nuclear receptor coactivator 1, Nuclear receptor subfamily 1 group I member 2 | | 著者 | Lv, L, Lin, W, Chai, S.C, Zhang, Q, Chen, T. | | 登録日 | 2017-01-23 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.665 Å) | | 主引用文献 | SPA70 is a potent antagonist of human pregnane X receptor.
Nat Commun, 8, 2017
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5W5F
 | | Cryo-EM structure of the T4 tail tube | | 分子名称: | Tail tube protein gp19 | | 著者 | Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H. | | 登録日 | 2017-06-15 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit.
Structure, 25, 2017
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5VSO
 | | NMR structure of Ydj1 J-domain, a cytosolic Hsp40 from Saccharomyces cerevisiae | | 分子名称: | Yeast dnaJ protein 1 | | 著者 | Ciesielski, S.J, Tonelli, M, Lee, W, Cornilescu, G, Markley, J.L, Schilke, B.A, Ziegelhoffer, T, Craig, E.A. | | 登録日 | 2017-05-12 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Broadening the functionality of a J-protein/Hsp70 molecular chaperone system.
PLoS Genet., 13, 2017
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5YI8
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5YQA
 | | The crystal structure of CYP199A4 binding with 4-n-Propyl benzoic acid | | 分子名称: | 4-propylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... | | 著者 | Zhou, W, Zhang, T, Qiao, R, Bell, S, Coleman, T. | | 登録日 | 2017-11-06 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | The crystal structure of CYP199A4 binding with 4-n-Propyl benzoic acid
To Be Published
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7DW5
 | | Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites | | 分子名称: | BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 | | 著者 | Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. | | 登録日 | 2021-01-15 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
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5YP4
 | | Crystal structure of dipeptidyl peptidase IV (DPP IV) with Lys-Pro from Pseudoxanthomonas mexicana WO24 | | 分子名称: | Dipeptidyl aminopeptidase 4, GLYCEROL, LYSINE, ... | | 著者 | Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T. | | 登録日 | 2017-11-01 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues.
Sci Rep, 8, 2018
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7E2Q
 | | Crystal structure of Mycoplasma pneumoniae Enolase | | 分子名称: | Enolase, SULFATE ION | | 著者 | Chen, R, Zhang, S, Gan, R, Wang, W, Ran, T, Xiong, Q, Shao, G, Feng, Z. | | 登録日 | 2021-02-07 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases.
Front Mol Biosci, 8, 2022
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5Y29
 | | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | | 著者 | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | | 登録日 | 2017-07-24 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects
J. Biol. Chem., 293, 2018
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5VRQ
 | | Crystal structure of Legionella pneumophila effector AnkC | | 分子名称: | Ankyrin repeat-containing protein | | 著者 | Kozlov, G, Wong, K, Wang, W, Skubak, P, Munoz-Escobar, J, Liu, Y, Pannu, N.S, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2017-05-11 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.205 Å) | | 主引用文献 | Ankyrin repeats as a dimerization module.
Biochem. Biophys. Res. Commun., 495, 2018
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5VZY
 | | Crystal structure of crenezumab Fab in complex with Abeta | | 分子名称: | Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain | | 著者 | Ultsch, M, Wang, W. | | 登録日 | 2017-05-29 | | 公開日 | 2017-08-09 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
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5W51
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5WT1
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5WZZ
 | | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation | | 分子名称: | Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION | | 著者 | Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. | | 登録日 | 2017-01-19 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
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5WU0
 | | Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | | 登録日 | 2016-12-15 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin
PLoS ONE, 12, 2017
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5YIM
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5YJD
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5YP1
 | | Crystal structure of dipeptidyl peptidase IV (DPP IV) from Pseudoxanthomonas mexicana WO24 | | 分子名称: | Dipeptidyl aminopeptidase 4, GLYCEROL | | 著者 | Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T. | | 登録日 | 2017-11-01 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues.
Sci Rep, 8, 2018
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5YET
 | | Structure of R354_WT | | 分子名称: | Uncharacterized protein R354 | | 著者 | Dou, C, Yu, M.J, Gu, Y.J, Cheng, W. | | 登録日 | 2017-09-19 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System.
Iscience, 3, 2018
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5YF6
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5Y1Z
 | | Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain | | 分子名称: | Drebrin, GLYCEROL, Protein kinase C-binding protein 1, ... | | 著者 | Yao, N, Li, J, Liu, H, Wan, J, Liu, W, Zhang, M. | | 登録日 | 2017-07-22 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.676 Å) | | 主引用文献 | The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin
Structure, 25, 2017
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