5X0R
Crystal Structure of PXR LBD Complexed with SJB7
Summary for 5X0R
Entry DOI | 10.2210/pdb5x0r/pdb |
Descriptor | Nuclear receptor subfamily 1 group I member 2, Nuclear receptor coactivator 1, 4-[(4-tert-butylphenyl)sulfonyl]-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole, ... (4 entities in total) |
Functional Keywords | transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : O75469 Q15788 |
Total number of polymer chains | 4 |
Total formula weight | 78888.87 |
Authors | Lv, L.,Lin, W.,Chai, S.C.,Zhang, Q.,Chen, T. (deposition date: 2017-01-23, release date: 2017-10-04, Last modification date: 2023-10-04) |
Primary citation | Lin, W.,Wang, Y.M.,Chai, S.C.,Lv, L.,Zheng, J.,Wu, J.,Zhang, Q.,Wang, Y.D.,Griffin, P.R.,Chen, T. SPA70 is a potent antagonist of human pregnane X receptor. Nat Commun, 8:741-741, 2017 Cited by PubMed: 28963450DOI: 10.1038/s41467-017-00780-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.665 Å) |
Structure validation
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