3J79
 
 | | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | | 登録日 | 2014-06-02 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
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8A2S
 | | Cryo-EM structure of F-actin in the Mg2+-ADP-Pi nucleotide state. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | | 登録日 | 2022-06-06 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.22 Å) | | 主引用文献 | Structural basis of actin filament assembly and aging.
Nature, 611, 2022
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1NMN
 | | Structure of yqgF from Escherichia coli, a hypothetical protein | | 分子名称: | Hypothetical protein yqgF | | 著者 | Galkin, A, Sarikaya, E, Krajewski, W, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | | 登録日 | 2003-01-10 | | 公開日 | 2004-03-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of yqgF from Escherichia coli, a hypothetical protein
To be Published
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2KID
 | | Solution Structure of the S. Aureus Sortase A-substrate Complex | | 分子名称: | (PHQ)LPA(B27) peptide, CALCIUM ION, Sortase | | 著者 | Suree, N, Liew, C.K, Villareal, V.A, Thieu, W, Fadeev, E.A, Clemens, J.J, Jung, M.E, Clubb, R.T. | | 登録日 | 2009-05-01 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized.
J.Biol.Chem., 284, 2009
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8A2R
 | | Cryo-EM structure of F-actin in the Mg2+-ADP-BeF3- nucleotide state. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | | 登録日 | 2022-06-06 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.17 Å) | | 主引用文献 | Structural basis of actin filament assembly and aging.
Nature, 611, 2022
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1NPR
 | | CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN C222(1) | | 分子名称: | Transcription antitermination protein nusG | | 著者 | Knowlton, J.R, Bubunenko, M, Andrykovitch, M, Guo, W, Routzhan, K.M, Waugh, D.S, Court, D.L, Ji, X. | | 登録日 | 2003-01-18 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by
Site-Directed Mutants
Biochemistry, 42, 2003
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3JAF
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state | | 分子名称: | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.801 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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1NQV
 | | Crystal Structure of Lumazine Synthase from Aquifex aeolicus in Complex with Inhibitor: 5-nitroso-6-ribityl-amino-2,4(1H,3H)pyrimidinedione | | 分子名称: | 5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | | 著者 | Zhang, X, Meining, W, Cushman, M, Haase, I, Fischer, M, Bacher, A, Ladenstein, R. | | 登録日 | 2003-01-23 | | 公開日 | 2004-01-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.
J.Mol.Biol., 328, 2003
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3F4V
 | | Semi-active E176Q mutant of rice BGlu1, a plant exoglucanase/beta-glucosidase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase, GLYCEROL, ... | | 著者 | Chuenchor, W, Ketudat Cairns, J.R, Pengthaisong, S, Robinson, R.C, Yuvaniyama, J, Chen, C.-J. | | 登録日 | 2008-11-03 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase
J.Struct.Biol., 173, 2011
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3JAU
 | | The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5 | | 分子名称: | Capsid protein VP1, Heavy chain of Fab fragment variable region of antibody D5, Light chain of Fab fragment variable region of antibody D5 | | 著者 | Fan, C, Ye, X.H, Ku, Z.Q, Zuo, T, Kong, L.L, Zhang, C, Shi, J.P, Liu, Q.W, Chen, T, Zhang, Y.Y, Jiang, W, Zhang, L.Q, Huang, Z, Cong, Y. | | 登録日 | 2015-06-24 | | 公開日 | 2016-02-10 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody
Plos Pathog., 12, 2016
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2K9X
 | | Solution structure of Urm1 from Trypanosoma brucei | | 分子名称: | Uncharacterized protein | | 著者 | Zhang, W, Zhang, J, Xu, C, Wang, T, Zhang, X, Tu, X. | | 登録日 | 2008-10-27 | | 公開日 | 2009-03-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Urm1 from Trypanosoma brucei
Proteins, 75, 2009
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3JB6
 | | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ... | | 著者 | Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H. | | 登録日 | 2015-08-02 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
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1NTH
 | | Crystal structure of the methanosarcina barkeri monomethylamine methyltransferase (MTMB) | | 分子名称: | Monomethylamine methyltransferase mtmB1 | | 著者 | Hao, B, Gong, W, Ferguson, T.K, James, C.M, Krzycki, J.A, Chan, M.K. | | 登録日 | 2003-01-30 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A new UAG-encoded residue in the structure of a methanogen methyltransferase
Science, 296, 2002
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3J46
 | | Structure of the SecY protein translocation channel in action | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L23P, ... | | 著者 | Akey, C.W, Park, E, Menetret, J.F, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A. | | 登録日 | 2013-06-18 | | 公開日 | 2013-10-23 | | 最終更新日 | 2019-07-03 | | 実験手法 | ELECTRON MICROSCOPY (10.1 Å) | | 主引用文献 | Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
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3F9R
 | | Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370 | | 分子名称: | MAGNESIUM ION, Phosphomannomutase, SULFATE ION | | 著者 | Wernimont, A.K, Lam, A, Ali, A, Lin, Y.H, Guther, L, Shamshad, A, MacKenzie, F, Bandini, G, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-14 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370
To be Published
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2K6Q
 | | LC3 p62 complex structure | | 分子名称: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | | 著者 | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | 登録日 | 2008-07-17 | | 公開日 | 2008-09-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
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3KJQ
 | | Caspase 8 with covalent inhibitor | | 分子名称: | (3S)-3-({[(5S,8R)-2-(3-carboxypropyl)-8-(2-{[(4-chlorophenyl)acetyl]amino}ethyl)-1,3-dioxo-2,3,5,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazin-5-yl]carbonyl}amino)-4-oxopentanoic acid, Caspase-8 | | 著者 | Kamtekar, S, Watt, W, Finzel, B.C, Harris, M.S, Blinn, J, Wang, Z, Tomasselli, A.G. | | 登録日 | 2009-11-03 | | 公開日 | 2010-08-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors.
Biochim.Biophys.Acta, 1804, 2010
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1PXY
 | | Crystal structure of the actin-crosslinking core of Arabidopsis fimbrin | | 分子名称: | fimbrin-like protein | | 著者 | Klein, M.G, Shi, W, Tseng, Y, Wirtz, D, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2003-07-07 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the actin crosslinking core of fimbrin.
Structure, 12, 2004
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1Q1G
 | | Crystal structure of Plasmodium falciparum PNP with 5'-methylthio-immucillin-H | | 分子名称: | 3,4-DIHYDROXY-2-[(METHYLSULFANYL)METHYL]-5-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)PYRROLIDINIUM, ISOPROPYL ALCOHOL, SULFATE ION, ... | | 著者 | Shi, W, Ting, L.M, Kicska, G.A, Lewandowicz, A, Tyler, P.C, Evans, G.B, Furneaux, R.H, Kim, K, Almo, S.C, Schramm, V.L. | | 登録日 | 2003-07-19 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.
J.Biol.Chem., 279, 2004
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7Z6L
 | | Crystal structure of PROTAC 5 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[3-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]propoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Roy, M.J, Bader, G, Farnaby, W, Ciulli, A. | | 登録日 | 2022-03-12 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.
Nat Commun, 13, 2022
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1Q2S
 | | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate | | 分子名称: | 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, ... | | 著者 | Xie, W, Liu, X, Huang, R.H. | | 登録日 | 2003-07-25 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
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3FEG
 | | Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide | | 分子名称: | (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-29 | | 公開日 | 2008-12-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
J.Biol.Chem., 285, 2010
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1Q5B
 | | lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | He, W, Cowin, P, Stokes, D.L. | | 登録日 | 2003-08-06 | | 公開日 | 2003-10-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (30 Å) | | 主引用文献 | Untangling Desmosomal Knots with Electron Tomography
Science, 302, 2003
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3KU4
 | | Trapping of an oxocarbenium ion intermediate in UP crystals | | 分子名称: | SULFATE ION, Uridine phosphorylase | | 著者 | Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. | | 登録日 | 2009-11-26 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
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2H17
 | | Structure of human ADP-ribosylation factor-like 5 (ARL5) | | 分子名称: | ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | | 著者 | Rabeh, W.M, Tempel, W, Yaniw, D, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-16 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of human ADP-ribosylation factor-like 5 (ARL5)
To be Published
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