1NQV
Crystal Structure of Lumazine Synthase from Aquifex aeolicus in Complex with Inhibitor: 5-nitroso-6-ribityl-amino-2,4(1H,3H)pyrimidinedione
Summary for 1NQV
Entry DOI | 10.2210/pdb1nqv/pdb |
Related | 1NQU 1NQW 1NQX |
Descriptor | 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION, 5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, ... (4 entities in total) |
Functional Keywords | lumazine synthase, aquifex aeolicus, inhibitor complex, vitamin biosynthesis, catalytic mechanism, transferase |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 5 |
Total formula weight | 85562.01 |
Authors | Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R. (deposition date: 2003-01-23, release date: 2004-01-23, Last modification date: 2024-02-14) |
Primary citation | Zhang, X.,Meining, W.,Cushman, M.,Haase, I.,Fischer, M.,Bacher, A.,Ladenstein, R. A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus. J.Mol.Biol., 328:167-182, 2003 Cited by PubMed: 12684006DOI: 10.1016/S0022-2836(03)00186-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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