8A78
 
 | | PcIDS1_F315A in complex with Mg2+/Mn2+ and GPP | | 分子名称: | GERANYL DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... | | 著者 | Ecker, F, Boland, W, Groll, M. | | 登録日 | 2022-06-20 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023
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8A70
 | | PcIDS1 in complex with Mg2+ and GPP | | 分子名称: | GERANYL DIPHOSPHATE, Isoprenyl diphosphate synthase, MAGNESIUM ION | | 著者 | Ecker, F, Boland, W, Groll, M. | | 登録日 | 2022-06-20 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Nat.Chem., 15, 2023
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8A74
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2ICK
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1ODV
 | | Photoactive yellow protein 1-25 deletion mutant | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Vreede, J, Van Der horst, M.A, Hellingwerf, K.J, Crielaard, W, Van Aalten, D.M.F. | | 登録日 | 2003-03-14 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Pas Domains.Common Structure and Common Flexibility
J.Biol.Chem., 278, 2003
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1O7E
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2IG7
 | | Crystal structure of Human Choline Kinase B | | 分子名称: | Choline/ethanolamine kinase, UNKNOWN ATOM OR ION | | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-09-22 | | 公開日 | 2006-10-10 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Human Choline Kinase B
To be Published
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2J1D
 | | Crystallization of hDaam1 C-terminal Fragment | | 分子名称: | DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1, GLYCEROL, PHOSPHATE ION | | 著者 | Lu, J, Meng, W, Poy, F, Eck, M.J. | | 登録日 | 2006-08-10 | | 公開日 | 2007-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of the Fh2 Domain of Daam1: Implications for Formin Regulation of Actin Assembly.
J.Mol.Biol., 369, 2007
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3DSH
 | | Crystal structure of dimeric interferon regulatory factor 5 (IRF-5) transactivation domain | | 分子名称: | Interferon regulatory factor 5 | | 著者 | Chen, W, Lam, S.S, Srinath, H, Jiang, Z, Correia, J.J, Schiffer, C, Fitzgerald, K.A, Lin, K, Royer Jr, W.E. | | 登録日 | 2008-07-12 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Nat.Struct.Mol.Biol., 15, 2008
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3DSU
 | | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with farnesyl pyrophosphate | | 分子名称: | CALCIUM ION, FARNESYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit alpha, ... | | 著者 | Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. | | 登録日 | 2008-07-14 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
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8A24
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3J7A
 | | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | | 著者 | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | | 登録日 | 2014-06-03 | | 公開日 | 2014-07-16 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
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8A25
 | | Lysophospholipase PlaA from Legionella pneumophila str. Corby - complex with PEG fragment | | 分子名称: | (R,R)-2,3-BUTANEDIOL, IODIDE ION, Lysophospholipase A, ... | | 著者 | Diwo, M.G, Blankenfeldt, W. | | 登録日 | 2022-06-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA.
Mol.Microbiol., 121, 2024
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8A26
 | | Lysophospholipase PlaA from Legionella pneumophila str. Corby - complex with palmitate | | 分子名称: | (R,R)-2,3-BUTANEDIOL, Lysophospholipase A, MALONIC ACID, ... | | 著者 | Diwo, M.G, Blankenfeldt, W. | | 登録日 | 2022-06-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA.
Mol.Microbiol., 121, 2024
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2HB1
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3DY0
 | | Crystal Structure of Cleaved PCI Bound to Heparin | | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ... | | 著者 | Li, W, Huntington, J.A. | | 登録日 | 2008-07-25 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The heparin binding site of protein C inhibitor is protease-dependent.
J.Biol.Chem., 283, 2008
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3K5N
 | | Crystal structure of E.coli Pol II-abasic DNA binary complex | | 分子名称: | DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II | | 著者 | Yang, W, Wang, F. | | 登録日 | 2009-10-07 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
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3DZQ
 | | Human EphA3 kinase domain in complex with inhibitor AWL-II-38.3 | | 分子名称: | EPH receptor A3, N-[2-methyl-5-({[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide | | 著者 | Walker, J.R, Syeda, F, Gray, N, Mansoor, W, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-07-30 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Kinase Domain of Human Ephrin Type-A Receptor 3 (Epha3) in Complex with ALW-II-38-3.
To be Published
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2HEH
 | | Crystal Structure of the KIF2C motor domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KIF2C protein, MAGNESIUM ION, ... | | 著者 | Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-06-21 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of the kif2c motor domain
to be published
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1OPK
 | | Structural basis for the auto-inhibition of c-Abl tyrosine kinase | | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | 著者 | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | | 登録日 | 2003-03-06 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
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2GTT
 | | Crystal structure of the rabies virus nucleoprotein-RNA complex | | 分子名称: | Nucleoprotein, PHOSPHATE ION, RNA (99-MER) | | 著者 | Albertini, A.A.V, Wernimont, A.K, Muziol, T, Ravelli, R.B.G, Weissenhorn, W, Ruigrok, R.W.H. | | 登録日 | 2006-04-28 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex
Science, 313, 2006
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3J9Z
 | | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J. | | 登録日 | 2015-03-27 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
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2HI9
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3JAV
 | | Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM | | 分子名称: | Inositol 1,4,5-trisphosphate receptor type 1 | | 著者 | Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I. | | 登録日 | 2015-06-30 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Gating machinery of InsP3R channels revealed by electron cryomicroscopy.
Nature, 527, 2015
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3JBT
 | | Atomic structure of the Apaf-1 apoptosome | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | | 著者 | Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y. | | 登録日 | 2015-10-15 | | 公開日 | 2015-11-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
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