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PDB: 34568 results

3B9H
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E. coli thymidylate synthase complexed with 5-NITRO-2'-DEOXY URIDINE
Descriptor: 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, PHOSPHATE ION, Thymidylate synthase
Authors:Roberts, S.A, Montfort, W.R.
Deposit date:2007-11-05
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural Studies of Early Events in the Thymidylate Synthase Reaction
To be Published
8J0D
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BU of 8j0d by Molmil
FCP heterodimer, Lhca2, and Lhcf5 together as the M1 side binds to the PSII core in the diatom Thalassiosira pseudonana
Descriptor: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
Authors:Li, Z, Feng, Y, Wang, W, Shen, J.R.
Deposit date:2023-04-10
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of a diatom photosystem II supercomplex containing a member of Lhcx family and dimeric FCPII.
Sci Adv, 9, 2023
3UWP
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Crystal structure of Dot1l in complex with 5-iodotubercidin
Descriptor: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ...
Authors:Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-02
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Nat Commun, 3, 2012
1CVH
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BU of 1cvh by Molmil
STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1994-11-16
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural consequences of redesigning a protein-zinc binding site.
Biochemistry, 33, 1994
3UV6
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BU of 3uv6 by Molmil
Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)
Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxybutyl trihydrogen diphosphate, IRON/SULFUR CLUSTER
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-11-29
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
1CVD
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BU of 1cvd by Molmil
STRUCTURAL CONSEQUENCES OF REDESIGNING A PROTEIN-ZINC BINDING SITE
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1994-06-21
Release date:1994-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural consequences of redesigning a protein-zinc binding site.
Biochemistry, 33, 1994
3UWM
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BU of 3uwm by Molmil
Ec_IspH in complex with 4-oxobutyl diphosphate (1302)
Descriptor: (3E)-4-hydroxybut-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-oxobutyl trihydrogen diphosphate, ...
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-12-02
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
8JFN
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BU of 8jfn by Molmil
Crystal structure of enoyl-ACP reductase FabI in complex with NAD+ and crotonyl-ACP from Helicobacter pylori
Descriptor: Acyl carrier protein, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Song, W.Y, Zhang, L.
Deposit date:2023-05-18
Release date:2023-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
Angew.Chem.Int.Ed.Engl., 62, 2023
2W4F
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BU of 2w4f by Molmil
CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1
Descriptor: 1,2-ETHANEDIOL, PROTEIN LAP4
Authors:Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U.
Deposit date:2008-11-25
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
8JFJ
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BU of 8jfj by Molmil
Crystal structure of enoyl-ACP reductase FabI from Helicobacter pylori
Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH]
Authors:Song, W.Y, Zhang, L.
Deposit date:2023-05-18
Release date:2023-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
Angew.Chem.Int.Ed.Engl., 62, 2023
3AZZ
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BU of 3azz by Molmil
Crystal structure of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with gluconolactone
Descriptor: CALCIUM ION, D-glucono-1,5-lactone, Laminarinase, ...
Authors:Jeng, W.Y, Wang, N.C, Wang, A.H.J.
Deposit date:2011-06-03
Release date:2011-11-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for beta-1,3 and beta-1,4 glucan selection.
J.Biol.Chem., 286, 2011
1DWE
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BU of 1dwe by Molmil
Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Descriptor: ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Banner, D.W, Hadvary, P.
Deposit date:1992-08-19
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266, 1991
1UAK
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BU of 1uak by Molmil
Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition
Descriptor: S-ADENOSYLMETHIONINE, tRNA (Guanine-N(1)-)-methyltransferase
Authors:Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K.
Deposit date:2003-03-11
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition
EMBO J., 22, 2003
1CQ4
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BU of 1cq4 by Molmil
CI2 MUTANT WITH TETRAGLUTAMINE (MGQQQQGM) REPLACING MET59
Descriptor: PROTEIN (SERINE PROTEINASE INHIBITOR 2), SULFATE ION
Authors:Chen, Y.W, Stott, K.R.
Deposit date:1998-11-17
Release date:1998-11-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat.
Proc.Natl.Acad.Sci.USA, 96, 1999
2W4Q
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BU of 2w4q by Molmil
Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid
Descriptor: (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROSTAGLANDIN REDUCTASE 2, ...
Authors:Shafqat, N, Yue, W.W, Ugochukwu, E, Picaud, S, Niesen, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
Deposit date:2008-11-30
Release date:2009-01-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1
To be Published
1CIA
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BU of 1cia by Molmil
REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE
Descriptor: BETA-MERCAPTOETHANOL, CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION
Authors:Leslie, A.G.W, Gibbs, M.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33, 1994
3B9O
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BU of 3b9o by Molmil
long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN
Descriptor: Alkane monooxygenase, FLAVIN MONONUCLEOTIDE
Authors:Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z.
Deposit date:2007-11-06
Release date:2008-01-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
J.Mol.Biol., 376, 2008
3B9N
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BU of 3b9n by Molmil
Crystal structure of long-chain alkane monooxygenase (LadA)
Descriptor: Alkane monooxygenase
Authors:Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z.
Deposit date:2007-11-06
Release date:2008-01-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
J.Mol.Biol., 376, 2008
8DN2
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BU of 8dn2 by Molmil
Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, glycine-bound state 2(expanded open)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, GLYCINE, ...
Authors:Liu, X, Wang, W.
Deposit date:2022-07-10
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Asymmetric gating of a human hetero-pentameric glycine receptor.
Nat Commun, 14, 2023
8DN4
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BU of 8dn4 by Molmil
Cryo-EM structure of human Glycine Receptor alpha-1 beta heteromer, glycine-bound state3(desensitized state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-1, Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta, ...
Authors:Liu, X, Wang, W.
Deposit date:2022-07-10
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Asymmetric gating of a human hetero-pentameric glycine receptor.
Nat Commun, 14, 2023
8DN5
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BU of 8dn5 by Molmil
Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, glycine-bound state1(open state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, GLYCINE, ...
Authors:Liu, X, Wang, W.
Deposit date:2022-07-10
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Asymmetric gating of a human hetero-pentameric glycine receptor.
Nat Commun, 14, 2023
8DN3
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BU of 8dn3 by Molmil
Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Liu, X, Wang, W.
Deposit date:2022-07-10
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Asymmetric gating of a human hetero-pentameric glycine receptor.
Nat Commun, 14, 2023
1CNB
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BU of 1cnb by Molmil
COMPENSATORY PLASTIC EFFECTS IN THE REDESIGN OF PROTEIN-ZINC BINDING SITES
Descriptor: BETA-MERCAPTOETHANOL, CARBONIC ANHYDRASE II
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1994-06-13
Release date:1994-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural consequences of redesigning a protein-zinc binding site.
Biochemistry, 33, 1994
4A1U
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BU of 4a1u by Molmil
Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL
Descriptor: ALPHA-BETA-FOLDAMER 2C, BCL-2-LIKE PROTEIN 1, CHLORIDE ION, ...
Authors:Boersma, M.D, Haase, H.S, Kaufman, K.J, Horne, W.S, Lee, E.F, Clarke, O.B, Smith, B.J, Colman, P.M, Gellman, S.H, Fairlie, W.D.
Deposit date:2011-09-20
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Evaluation of Diverse Alpha/Beta-Backbone Patterns for Functional Alpha-Helix Mimicry: Analogues of the Bim Bh3 Domain.
J.Am.Chem.Soc., 134, 2012
1UAL
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BU of 1ual by Molmil
Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase
Authors:Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K.
Deposit date:2003-03-11
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition
EMBO J., 22, 2003

224004

数据于2024-08-21公开中

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