1CIA

REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE

Summary for 1CIA

DescriptorCHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION, BETA-MERCAPTOETHANOL, ... (4 entities in total)
Functional Keywordstransferase(acyltransferase)
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight25207.48
Authors
Leslie, A.G.W.,Gibbs, M.R. (deposition date: 1993-07-19, release date: 1994-01-31, Last modification date: 2011-07-13)
Primary citation
Lewendon, A.,Murray, I.A.,Shaw, W.V.,Gibbs, M.R.,Leslie, A.G.
Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33:1944-1950, 1994
PubMed: 7906544 (PDB entries with the same primary citation)
DOI: 10.1021/bi00173a043
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers705.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report