8JFN

Crystal structure of enoyl-ACP reductase FabI in complex with NAD+ and crotonyl-ACP from Helicobacter pylori

Summary for 8JFN

Entry DOI	10.2210/pdb8jfn/pdb
Descriptor	Enoyl-[acyl-carrier-protein] reductase [NADH], Acyl carrier protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	enoyl-acp reductase, fabi, nad+, crotonyl-acp, helicobacter pylori, biosynthetic protein
Biological source	Helicobacter pylori More
Total number of polymer chains	2
Total formula weight	39578.81
Authors	Song, W.Y.,Zhang, L. (deposition date: 2023-05-18, release date: 2023-11-15, Last modification date: 2023-11-22)
Primary citation	Zhou, J.,Zhang, L.,Wang, Y.,Song, W.,Huang, Y.,Mu, Y.,Schmitz, W.,Zhang, S.Y.,Lin, H.,Chen, H.Z.,Ye, F.,Zhang, L. The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis. Angew.Chem.Int.Ed.Engl., 62:e202313109-e202313109, 2023 Cited by PubMed: 37779101 DOI: 10.1002/anie.202313109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation