2W4Q

Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid

Summary for 2W4Q

• Entry DOI: 10.2210/pdb2w4q/pdb
• Descriptor: PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, ... (5 entities in total)
• Functional Keywords: 15-oxoprostalglandin, medium-chain dehydrogenase/reductase, nadp, oxidoreductase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 41400.73

Authors

Shafqat, N.,Yue, W.W.,Ugochukwu, E.,Picaud, S.,Niesen, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2008-11-30, release date: 2009-01-20, Last modification date: 2023-12-13)

• Primary citation: Shafqat, N.,Yue, W.W.,Niesen, F.,Oppermann, U.; Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)