2W4Q
Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROSTAGLANDIN REDUCTASE 2 | polymer | 357 | 39331.7 | 1 | UniProt (Q8N8N7) Pfam (PF16884) Pfam (PF00107) | HOMO SAPIENS (HUMAN) | 15-OXOPROSTAGLANDIN 13-REDUCTASE, ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 1, PRG-2, ZINC-BINDING ALCOHOL DEHYDROGENASE 1 |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 3 | C, D (A) | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID | non-polymer | 470.7 | 2 | Chemie (CBW) PubChem (16219451) PubChem (16757767) PubChem (16759277) PubChem (17751012) PubChem (18530175) PubChem (176519885) PubChem (23426892) PubChem (24126417) PubChem (24728667) PubChem (24840718) PubChem (24840722) PubChem (25796773) PubChem (42051909) PubChem (73398) PubChem (18526330) PubChem (21115234) PubChem (49828956) PubChem (125828) PubChem (28094590) PubChem (54084031) PubChem (54084032) PubChem (56609457) PubChem (44435791) PubChem (59271691) PubChem (59799942) PubChem (59799943) PubChem (440167) PubChem (67197437) PubChem (67523993) PubChem (67591316) PubChem (68265830) PubChem (53393510) PubChem (72947821) PubChem (86574228) PubChem (68219106) PubChem (70532701) PubChem (89950111) PubChem (89950117) PubChem (3230) PubChem (10114) PubChem (90658335) PubChem (112111) PubChem (5317760) PubChem (97182165) PubChem (98145201) PubChem (6604622) PubChem (124351362) PubChem (5702158) PubChem (5702287) PubChem (124721092) PubChem (129121397) PubChem (129460562) PubChem (129689801) PubChem (98092677) PubChem (98092680) PubChem (98092682) PubChem (98092683) PubChem (7067783) PubChem (7067786) PubChem (7067788) PubChem (7067790) PubChem (121334457) PubChem (11870318) PubChem (9826000) PubChem (9897771) PubChem (12310273) PubChem (124518075) PubChem (11751767) PubChem (11870316) PubChem (11870320) PubChem (11870322) PubChem (11870421) PubChem (11870423) PubChem (11870425) PubChem (124721091) PubChem (12097316) PubChem (12193680) PubChem (12310260) PubChem (12310262) PubChem (12310272) PubChem (12310275) PubChem (12310280) PubChem (12310282) PubChem (155900334) PubChem (162991546) PubChem (163781710) PubChem (129360478) PubChem (129447954) PubChem (133109089) PubChem (133568304) PubChem (133612083) PubChem (133685580) PubChem (134689057) PubChem (154515951) PubChem (156280553) PubChem (162991547) PubChem (162991548) PubChem (162991549) PubChem (162991550) PubChem (162991551) PubChem (162991552) PubChem (162991553) PubChem (162991554) PubChem (162991555) PubChem (170851295) PubChem (170924268) PubChem (171352479) | |||
| 4 | E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39331.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2069.0 | |
| All* | Total formula weight | 41400.7 |
