2W4Q
Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROSTAGLANDIN REDUCTASE 2 | polymer | 357 | 39331.7 | 1 | UniProt (Q8N8N7) Pfam (PF16884) Pfam (PF00107) | HOMO SAPIENS (HUMAN) | 15-OXOPROSTAGLANDIN 13-REDUCTASE, ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 1, PRG-2, ZINC-BINDING ALCOHOL DEHYDROGENASE 1 |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C, D (A) | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID | non-polymer | 470.7 | 2 | Chemie (CBW) | |||
| 4 | E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39331.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2069.0 | |
| All* | Total formula weight | 41400.7 |
