Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 115 results

5IH4
DownloadVisualize
BU of 5ih4 by Molmil
Human Casein Kinase 1 isoform delta apo (kinase domain)
Descriptor: Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, SULFATE ION, ...
Authors:Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
Deposit date:2016-02-29
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
5IH6
DownloadVisualize
BU of 5ih6 by Molmil
Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A derivative
Descriptor: 6-(3-bromophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ...
Authors:Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
Deposit date:2016-02-29
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
5IH5
DownloadVisualize
BU of 5ih5 by Molmil
Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A
Descriptor: 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ...
Authors:Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
Deposit date:2016-02-29
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
4I1M
DownloadVisualize
BU of 4i1m by Molmil
Crystal structure of the Legionella pneumophila GAP domain of LepB
Descriptor: DI(HYDROXYETHYL)ETHER, LepB
Authors:Streller, A, Gazdag, E.M, Vetter, I.R, Goody, R.S, Itzen, A.
Deposit date:2012-11-21
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.
Embo Rep., 14, 2013
4I1O
DownloadVisualize
BU of 4i1o by Molmil
Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3
Descriptor: BERYLLIUM TRIFLUORIDE ION, DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gazdag, E.M, Streller, A, Vetter, I.R, Goody, R.S, Itzen, A.
Deposit date:2012-11-21
Release date:2013-01-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.
Embo Rep., 14, 2013
1S1C
DownloadVisualize
BU of 1s1c by Molmil
Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ...
Authors:Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R.
Deposit date:2004-01-06
Release date:2004-02-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.
J.Biol.Chem., 279, 2004
1A4R
DownloadVisualize
BU of 1a4r by Molmil
G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM
Descriptor: AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rudolph, M.G, Vetter, I.R, Wittinghofer, A.
Deposit date:1998-02-02
Release date:1999-03-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.
Protein Sci., 8, 1999
3L8Y
DownloadVisualize
BU of 3l8y by Molmil
Complex of Ras with cyclen
Descriptor: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3LVQ
DownloadVisualize
BU of 3lvq by Molmil
The crystal structure of ASAP3 in complex with Arf6 in transition state
Descriptor: ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ...
Authors:Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A.
Deposit date:2010-02-22
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism
Cell(Cambridge,Mass.), 141, 2010
3L8Z
DownloadVisualize
BU of 3l8z by Molmil
H-Ras wildtype new crystal form
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3LVR
DownloadVisualize
BU of 3lvr by Molmil
The crystal structure of ASAP3 in complex with Arf6 in transition state soaked with Calcium
Descriptor: ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ...
Authors:Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A.
Deposit date:2010-02-22
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism
Cell(Cambridge,Mass.), 141, 2010
3KUD
DownloadVisualize
BU of 3kud by Molmil
Complex of Ras-GDP with RafRBD(A85K)
Descriptor: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M.
Deposit date:2009-11-27
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
J.Mol.Biol., 399, 2010
3KUC
DownloadVisualize
BU of 3kuc by Molmil
Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M.
Deposit date:2009-11-27
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
J.Mol.Biol., 399, 2010
1M5I
DownloadVisualize
BU of 1m5i by Molmil
Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
Descriptor: APC protein
Authors:Tickenbrock, L, Cramer, J, Vetter, I.R, Mueller, O.
Deposit date:2002-07-09
Release date:2002-11-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).
J.Biol.Chem., 277, 2002
1M7B
DownloadVisualize
BU of 1m7b by Molmil
Crystal structure of Rnd3/RhoE: functional implications
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rnd3/RhoE small GTP-binding protein
Authors:Fiegen, D, Blumenstein, L, Stege, P, Vetter, I.R, Ahmadian, M.R.
Deposit date:2002-07-19
Release date:2002-08-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Rnd3/RhoE: functional implications
FEBS LETT., 525, 2002
7QPG
DownloadVisualize
BU of 7qpg by Molmil
Human RZZ kinetochore corona complex.
Descriptor: Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog
Authors:Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A.
Deposit date:2022-01-04
Release date:2022-03-16
Last modified:2022-05-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores.
Embo J., 41, 2022
4F0G
DownloadVisualize
BU of 4f0g by Molmil
Crystal Structure of the Roco4 Kinase Domain from D. discoideum
Descriptor: Serine/threonine-protein kinase roco4
Authors:Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A.
Deposit date:2012-05-04
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F0F
DownloadVisualize
BU of 4f0f by Molmil
Crystal Structure of the Roco4 Kinase Domain bound to AppCp from D. discoideum
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4
Authors:Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A.
Deposit date:2012-05-04
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F1M
DownloadVisualize
BU of 4f1m by Molmil
Crystal Structure of the G1179S Roco4 Kinase Domain bound to AppCp from D. discoideum.
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A.
Deposit date:2012-05-07
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F1O
DownloadVisualize
BU of 4f1o by Molmil
Crystal Structure of the L1180T mutant Roco4 Kinase Domain from D. discoideum bound to AppCp
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4
Authors:Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A.
Deposit date:2012-05-07
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F1T
DownloadVisualize
BU of 4f1t by Molmil
Crystal Structure of the Roco4 Kinase Domain from D. discoideum bound to the ROCK Inhibitor H1152
Descriptor: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, Serine/threonine-protein kinase roco4
Authors:Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A.
Deposit date:2012-05-07
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
3U0V
DownloadVisualize
BU of 3u0v by Molmil
Crystal Structure Analysis of human LYPLAL1
Descriptor: Lysophospholipase-like protein 1
Authors:Burger, M, Zimmermann, T.J, Kondoh, Y, Stege, P, Watanabe, N, Osada, H, Waldmann, H, Vetter, I.R.
Deposit date:2011-09-29
Release date:2011-11-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases
J.Lipid Res., 53, 2012
3T1O
DownloadVisualize
BU of 3t1o by Molmil
MglA bound to GDP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA, ...
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T1V
DownloadVisualize
BU of 3t1v by Molmil
MglA bound to GDP in P2(1) tetrameric arrangement
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA
Authors:Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
Deposit date:2011-07-22
Release date:2011-08-31
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
6EQT
DownloadVisualize
BU of 6eqt by Molmil
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE PROTEIN CENP-N
Descriptor: Centromere protein N
Authors:Pentakota, S, Vetter, I.R, Petrovic, A, Musacchio, A.
Deposit date:2017-10-15
Release date:2018-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.735 Å)
Cite:Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017

221371

數據於2024-06-19公開中

PDB statisticsPDBj update infoContact PDBjnumon