7QPG
| Human RZZ kinetochore corona complex. | 分子名称: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | 著者 | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | 登録日 | 2022-01-04 | 公開日 | 2022-03-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. Embo J., 41, 2022
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1A4R
| G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | 分子名称: | AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Rudolph, M.G, Vetter, I.R, Wittinghofer, A. | 登録日 | 1998-02-02 | 公開日 | 1999-03-02 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal. Protein Sci., 8, 1999
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4O9Y
| Crystal Structure of TcdA1 | 分子名称: | TcdA1 | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | 登録日 | 2014-01-03 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
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4O9X
| Crystal Structure of TcdB2-TccC3 | 分子名称: | MERCURY (II) ION, TcdB2, TccC3 | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | 登録日 | 2014-01-03 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
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4QAM
| Crystal Structure of the RPGR RCC1-like domain in complex with the RPGR-interacting domain of RPGRIP1 | 分子名称: | GLYCEROL, MAGNESIUM ION, X-linked retinitis pigmentosa GTPase regulator, ... | 著者 | Remans, K, Buerger, M, Vetter, I.R, Wittinghofer, A. | 登録日 | 2014-05-05 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | C2 domains as protein-protein interaction modules in the ciliary transition zone. Cell Rep, 8, 2014
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4QNQ
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4I1M
| Crystal structure of the Legionella pneumophila GAP domain of LepB | 分子名称: | DI(HYDROXYETHYL)ETHER, LepB | 著者 | Streller, A, Gazdag, E.M, Vetter, I.R, Goody, R.S, Itzen, A. | 登録日 | 2012-11-21 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. Embo Rep., 14, 2013
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4I1O
| Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3 | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Gazdag, E.M, Streller, A, Vetter, I.R, Goody, R.S, Itzen, A. | 登録日 | 2012-11-21 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. Embo Rep., 14, 2013
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3L8Y
| Complex of Ras with cyclen | 分子名称: | 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ... | 著者 | Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R. | 登録日 | 2010-01-04 | 公開日 | 2011-01-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49, 2010
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3L8Z
| H-Ras wildtype new crystal form | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R. | 登録日 | 2010-01-04 | 公開日 | 2011-01-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49, 2010
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3LVQ
| The crystal structure of ASAP3 in complex with Arf6 in transition state | 分子名称: | ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ... | 著者 | Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A. | 登録日 | 2010-02-22 | 公開日 | 2010-06-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism Cell(Cambridge,Mass.), 141, 2010
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3KUD
| Complex of Ras-GDP with RafRBD(A85K) | 分子名称: | GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M. | 登録日 | 2009-11-27 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. J.Mol.Biol., 399, 2010
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3KUC
| Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R) | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M. | 登録日 | 2009-11-27 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. J.Mol.Biol., 399, 2010
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3LVR
| The crystal structure of ASAP3 in complex with Arf6 in transition state soaked with Calcium | 分子名称: | ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ... | 著者 | Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A. | 登録日 | 2010-02-22 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism Cell(Cambridge,Mass.), 141, 2010
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1M7B
| Crystal structure of Rnd3/RhoE: functional implications | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rnd3/RhoE small GTP-binding protein | 著者 | Fiegen, D, Blumenstein, L, Stege, P, Vetter, I.R, Ahmadian, M.R. | 登録日 | 2002-07-19 | 公開日 | 2002-08-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Rnd3/RhoE: functional implications FEBS LETT., 525, 2002
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1M5I
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6EZT
| Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase D437A inactive mutant from Vibrio harveyi | 分子名称: | Beta-N-acetylglucosaminidase Nag2, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | 著者 | Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W. | 登録日 | 2017-11-16 | 公開日 | 2018-12-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi To Be Published
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6EZR
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6EZS
| Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi in complex with N-acetylglucosamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylglucosaminidase Nag2, MALONATE ION | 著者 | Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W. | 登録日 | 2017-11-16 | 公開日 | 2018-12-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi To Be Published
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6EQT
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4F0G
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4F0F
| Crystal Structure of the Roco4 Kinase Domain bound to AppCp from D. discoideum | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4 | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | 登録日 | 2012-05-04 | 公開日 | 2012-06-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F1M
| Crystal Structure of the G1179S Roco4 Kinase Domain bound to AppCp from D. discoideum. | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | 登録日 | 2012-05-07 | 公開日 | 2012-06-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F1O
| Crystal Structure of the L1180T mutant Roco4 Kinase Domain from D. discoideum bound to AppCp | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4 | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | 登録日 | 2012-05-07 | 公開日 | 2012-06-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F1T
| Crystal Structure of the Roco4 Kinase Domain from D. discoideum bound to the ROCK Inhibitor H1152 | 分子名称: | (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, Serine/threonine-protein kinase roco4 | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | 登録日 | 2012-05-07 | 公開日 | 2012-06-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc.Natl.Acad.Sci.USA, 109, 2012
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