2C4N
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![BU of 2c4n by Molmil](/molmil-images/mine/2c4n) | NagD from E.coli K-12 strain | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, PROTEIN NAGD | 著者 | Tremblay, L.W, Dunaway-Mariano, D, Allen, K. | 登録日 | 2005-10-20 | 公開日 | 2006-01-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Activity Analyses of Escherichia Coli K-12 Nagd Provide Insight Into the Evolution of Biochemical Function in the Haloalkanoic Acid Dehalogenase Superfamily Biochemistry, 45, 2006
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3DWZ
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![BU of 3dwz by Molmil](/molmil-images/mine/3dwz) | Meropenem Covalent Adduct with TB Beta-lactamase | 分子名称: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Hugonnet, J.E, Blanchard, J.S. | 登録日 | 2008-07-23 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis Science, 323, 2009
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3C8Z
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![BU of 3c8z by Molmil](/molmil-images/mine/3c8z) | The 1.6 A Crystal Structure of MshC: The Rate Limiting Enzyme in the Mycothiol Biosynthetic Pathway | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Cysteinyl-tRNA synthetase, ... | 著者 | Tremblay, L.W, Fan, F, Vetting, M.W, Blanchard, J.S. | 登録日 | 2008-02-14 | 公開日 | 2008-12-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway. Biochemistry, 47, 2008
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3CG5
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![BU of 3cg5 by Molmil](/molmil-images/mine/3cg5) | |
3HT5
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![BU of 3ht5 by Molmil](/molmil-images/mine/3ht5) | |
3IQA
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![BU of 3iqa by Molmil](/molmil-images/mine/3iqa) | Crystal Structure of BlaC covalently bound with Doripenem | 分子名称: | (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Blanchard, J.S. | 登録日 | 2009-08-19 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry, 49, 2010
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1Z4N
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![BU of 1z4n by Molmil](/molmil-images/mine/1z4n) | Structure of beta-phosphoglucomutase with inhibitor bound alpha-galactose 1-phosphate cocrystallized with Fluoride | 分子名称: | 1-O-phosphono-alpha-D-galactopyranose, Beta-phosphoglucomutase, MAGNESIUM ION | 著者 | Tremblay, L.W, Zhang, G, Dai, J, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2005-03-16 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Chemical Confirmation of a Pentavalent Phosphorane in Complex with beta-Phosphoglucomutase J.Am.Chem.Soc., 127, 2005
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1Z4O
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![BU of 1z4o by Molmil](/molmil-images/mine/1z4o) | Structure of beta-phosphoglucomutase with inhibitor bound alpha-galactose 1-phosphate | 分子名称: | 1-O-phosphono-alpha-D-galactopyranose, Beta-phosphoglucomutase, MAGNESIUM ION | 著者 | Tremblay, L.W, Zhang, G, Dai, J, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2005-03-16 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Chemical Confirmation of a Pentavalent Phosphorane in Complex with beta-Phosphoglucomutase J.Am.Chem.Soc., 127, 2005
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3N8R
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![BU of 3n8r by Molmil](/molmil-images/mine/3n8r) | |
3NC8
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![BU of 3nc8 by Molmil](/molmil-images/mine/3nc8) | |
3NY4
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![BU of 3ny4 by Molmil](/molmil-images/mine/3ny4) | Crystal Structure of BlaC-K73A bound with Cefamandole | 分子名称: | (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Blanchard, J.S. | 登録日 | 2010-07-14 | 公開日 | 2010-11-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Structures of the Michaelis Complex (1.2 A) and the Covalent Acyl Intermediate (2.0 A) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis beta-Lactamase K73A and E166A Mutants. Biochemistry, 49, 2010
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3M6H
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![BU of 3m6h by Molmil](/molmil-images/mine/3m6h) | Crystal Structure of Post-isomerized Ertapenem Covalent Adduct with TB B-lactamase | 分子名称: | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W. | 登録日 | 2010-03-15 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | 主引用文献 | Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry, 49, 2010
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3N7W
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![BU of 3n7w by Molmil](/molmil-images/mine/3n7w) | |
3NDE
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![BU of 3nde by Molmil](/molmil-images/mine/3nde) | |
3NCK
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![BU of 3nck by Molmil](/molmil-images/mine/3nck) | |
3N8S
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![BU of 3n8s by Molmil](/molmil-images/mine/3n8s) | Crystal Structure of BlaC-E166A covalently bound with Cefamandole | 分子名称: | (2R)-2-[(1R)-1-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-2-oxoethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Blanchard, J.S. | 登録日 | 2010-05-28 | 公開日 | 2010-11-24 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the Michaelis Complex (1.2 A) and the Covalent Acyl Intermediate (2.0 A) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis beta-Lactamase K73A and E166A Mutants. Biochemistry, 49, 2010
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3N6I
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![BU of 3n6i by Molmil](/molmil-images/mine/3n6i) | |
3NDG
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![BU of 3ndg by Molmil](/molmil-images/mine/3ndg) | |
3NBL
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![BU of 3nbl by Molmil](/molmil-images/mine/3nbl) | |
3N8L
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![BU of 3n8l by Molmil](/molmil-images/mine/3n8l) | |
3M6B
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![BU of 3m6b by Molmil](/molmil-images/mine/3m6b) | Crystal Structure of the Ertapenem Pre-isomerized Covalent Adduct with TB B-lactamase | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Fan, F, Blanchard, J.S. | 登録日 | 2010-03-15 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. Biochemistry, 49, 2010
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1ZOL
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![BU of 1zol by Molmil](/molmil-images/mine/1zol) | native beta-PGM | 分子名称: | MAGNESIUM ION, beta-phosphoglucomutase | 著者 | Zhang, G, Tremblay, L.W, Dai, J, Wang, L, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2005-05-13 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis Biochemistry, 44, 2005
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