3C8Z

The 1.6 A Crystal Structure of MshC: The Rate Limiting Enzyme in the Mycothiol Biosynthetic Pathway

Summary for 3C8Z

• Entry DOI: 10.2210/pdb3c8z/pdb
• Related: 1li5 1u0b
• Descriptor: Cysteinyl-tRNA synthetase, ZINC ION, SULFATE ION, ... (7 entities in total)
• Functional Keywords: cysteine ligase, rossmann fold, cys-sa inhibitor, zinc binding, atp-binding, aminoacyl-trna synthetase, nucleotide-binding, protein biosynthesis, ligase
• Biological source: Mycobacterium smegmatis
• Total number of polymer chains: 2
• Total formula weight: 93524.49

Authors

Tremblay, L.W.,Fan, F.,Vetting, M.W.,Blanchard, J.S. (deposition date: 2008-02-14, release date: 2008-12-30, Last modification date: 2024-04-03)

• Primary citation: Tremblay, L.W.,Fan, F.,Vetting, M.W.,Blanchard, J.S.; The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway.; Biochemistry, 47:13326-13335, 2008; PubMed: 19053270; DOI: 10.1021/bi801708f

Experimental method

X-RAY DIFFRACTION (1.6 Å)