3NCK

Crystal Structure of BlaC-E166A covalently bound with Nafcillin

Summary for 3NCK

• Entry DOI: 10.2210/pdb3nck/pdb
• Descriptor: Beta-lactamase, (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (3 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28631.18

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-06-04, release date: 2011-12-14, Last modification date: 2023-09-06)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; BlaC-E166A covalently bound with cephalosporins and penicillins; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)