3CG5

Crystal Structure of the Covalent Adduct Formed between TB B-lactamase and Clavulanate

Summary for 3CG5

Entry DOI	10.2210/pdb3cg5/pdb
Descriptor	Beta-lactamase, PHOSPHATE ION, (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, ... (4 entities in total)
Functional Keywords	alpha-beta structure, covalent adduct, antibiotic resistance, hydrolase, lipoprotein, membrane, palmitate
Biological source	Mycobacterium tuberculosis
Cellular location	Cell membrane; Lipid-anchor (Potential): P0C5C1
Total number of polymer chains	1
Total formula weight	28809.77
Authors	Tremblay, L.W.,Hugonnet, J.E.,Blanchard, J.S. (deposition date: 2008-03-04, release date: 2008-05-27, Last modification date: 2023-08-30)
Primary citation	Tremblay, L.W.,Hugonnet, J.E.,Blanchard, J.S. Structure of the covalent adduct formed between Mycobacterium tuberculosis beta-lactamase and clavulanate. Biochemistry, 47:5312-5316, 2008 Cited by PubMed: 18422342 DOI: 10.1021/bi8001055 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation