3NBL

Crystal Structure of BlaC-E166A covalently bound with Cefuroxime

Summary for 3NBL

• Entry DOI: 10.2210/pdb3nbl/pdb
• Descriptor: Beta-lactamase, (2R)-5-[(carbamoyloxy)methyl]-2-[(1R)-1-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-2-oxoethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28641.09

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-06-03, release date: 2011-12-14, Last modification date: 2023-09-06)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; BlaC-E166A covalently bound with cephalosporins and penicillins; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)