3N8L

Crystal Structure of BlaC-E166A covalently bound with Ampicillin

Summary for 3N8L

• Entry DOI: 10.2210/pdb3n8l/pdb
• Descriptor: Beta-lactamase, PHOSPHATE ION, (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28756.05

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-05-28, release date: 2011-12-14, Last modification date: 2017-11-08)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; Structures of BlaC-E166A covalently bound to beta-lactams from all classes.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)