5CSK
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1ID4
| CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT (H157Q) OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | Descriptor: | CAPSID PROTEIN P40: ASSEMBLIN PROTEASE | Authors: | Khayat, R, Batra, R, Massariol, M.J, Lagace, L, Tong, L. | Deposit date: | 2001-04-03 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry, 40, 2001
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2B6E
| X-Ray Crystal Structure of Protein HI1161 from Haemophilus influenzae. Northeast Structural Genomics Consortium Target IR63. | Descriptor: | ACETIC ACID, Hypothetical UPF0152 protein HI1161 | Authors: | Kuzin, A.P, Benach, J, Chen, Y, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Kellie, R, Cunningham, K.E, Montelione, G, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-10-01 | Release date: | 2005-10-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-Ray structure of the different crystal form of the hypothetical UPF0152 protein HI1161: NESG target IR63 TO BE PUBLISHED
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4ILS
| Crystal structure of engineered protein. northeast structural genomics Consortium target or117 | Descriptor: | Engineered protein | Authors: | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-12-31 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of engineered protein. northeast structural genomics Consortium target or117 To be Published
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1PJL
| Crystal structure of human m-NAD-ME in ternary complex with NAD and Lu3+ | Descriptor: | LUTETIUM (III) ION, NAD-dependent malic enzyme, mitochondrial, ... | Authors: | Yang, Z, Batra, R, Floyd, D.L, Hung, H.-C, Chang, G.-G, Tong, L. | Deposit date: | 2003-06-03 | Release date: | 2003-06-17 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Potent and competitive inhibition of malic enzymes by lanthanide ions Biochem.Biophys.Res.Commun., 274, 2000
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1LXN
| X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 | Descriptor: | HYPOTHETICAL PROTEIN MTH1187, SULFATE ION | Authors: | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-06-05 | Release date: | 2003-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C Proteins, 52, 2003
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2EWO
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3USH
| Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 | Descriptor: | BROMIDE ION, Uncharacterized protein | Authors: | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-11-23 | Release date: | 2011-12-14 | Last modified: | 2018-06-13 | Method: | X-RAY DIFFRACTION (1.692 Å) | Cite: | Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 To be Published
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1PDW
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1NJT
| COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | Descriptor: | CHLORIDE ION, Capsid protein P40, Peptidomimetic Inhibitor | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-02 | Release date: | 2003-02-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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5VJ1
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1NKK
| COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | Descriptor: | Capsid protein P40, Peptidomimetic inhibitor | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-03 | Release date: | 2003-02-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1NXU
| CRYSTAL STRUCTURE OF E. COLI HYPOTHETICAL OXIDOREDUCTASE YIAK NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82. | Descriptor: | Hypothetical oxidoreductase yiaK, SULFATE ION | Authors: | Forouhar, F, Lee, I, Benach, J, Kulkarni, K, Xiao, R, Acton, T.B, Shastry, R, Rost, B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-11 | Release date: | 2003-03-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK). J.Biol.Chem., 279, 2004
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3E23
| Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299 | Descriptor: | S-ADENOSYLMETHIONINE, SULFATE ION, uncharacterized protein RPA2492 | Authors: | Forouhar, F, Chen, Y, Seetharaman, J, Mao, L, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-08-05 | Release date: | 2008-09-30 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the RPA2492 protein in complex with SAM from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR299 To be Published
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2OA5
| Crystal structure of ORF52 from Murid herpesvirus (MUHV-4) (Murine gammaherpesvirus 68) at 2.1 A resolution. Northeast Structural Genomics Consortium target MHR28B. | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Hypothetical protein BQLF2 | Authors: | Benach, J, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Ho, C.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-12-14 | Release date: | 2007-01-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of the abundant tegument protein ORF52 from murine gammaherpesvirus 68. J.Biol.Chem., 282, 2007
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3DTO
| Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130. | Descriptor: | BH2835 protein | Authors: | Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Cunningham, K, Ma, L.-C, Owen, L.A, Wang, D, Tong, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-07-15 | Release date: | 2008-09-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of the metal-dependent HD domain-containing hydrolase BH2835 from Bacillus halodurans, Northeast Structural Genomics Consortium Target BhR130. To be Published
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3VB8
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43 | Descriptor: | Engineered protein, SULFATE ION | Authors: | Seetharaman, J, Su, M, Procko, E, Baker, D, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-12-31 | Release date: | 2012-06-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Computational design of a protein-based enzyme inhibitor. J.Mol.Biol., 425, 2013
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4FJ4
| Crystal structure of the protein Q9HRE7 complexed with mercury from Halobacterium salinarium at the resolution 2.1A, Northeast Structural Genomics Consortium target HsR50 | Descriptor: | ETHYL MERCURY ION, SODIUM ION, Uncharacterized protein | Authors: | Kuzin, A, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Maglaqui, M, Owens, L.A, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-11 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Northeast Structural Genomics Consortium Target HsR50 To be Published
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1NY1
| CRYSTAL STRUCTURE OF B. SUBTILIS POLYSACCHARIDE DEACETYLASE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR127. | Descriptor: | Probable polysaccharide deacetylase pdaA | Authors: | Forouhar, F, Edstrom, W, Khan, J, Ma, L, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-11 | Release date: | 2003-03-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Polysaccharide Deacetylase (PDAA_BACSU) from B. Subtilis (Pdaa_Bacsu) Northeast Structural Genomics Research Consortium (Nesg) Target Sr127 To be Published
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4G63
| Crystal structure of cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) in complex with phosphate ions from Legionella pneumophila, Northeast Structural Genomics Consortium Target LgR1 | Descriptor: | Cytosolic IMP-GMP specific 5'-nucleotidase, PHOSPHATE ION | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Ho, C.K, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-07-18 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. Febs J., 281, 2014
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1PJ4
| Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, ATP, Mn++, and allosteric activator fumarate. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-MALATE, FUMARIC ACID, ... | Authors: | Tao, X, Yang, Z, Tong, L. | Deposit date: | 2003-05-31 | Release date: | 2003-09-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure, 11, 2003
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2DLB
| X-ray Crystal Structure of Protein yopT from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR412 | Descriptor: | yopT | Authors: | Kuzin, A.P, Chen, Y, Seetharaman, J, Ho, C.-K, Cunningham, K, Janjua, H, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-04-18 | Release date: | 2006-04-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | X-ray structure of hypothetical protein from Bacillus subtilis O34498 at the resolution of 1.2A. NESG target SR412 To be published
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4HFX
| Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. | Descriptor: | SULFATE ION, Transcription elongation factor B polypeptide 3 | Authors: | Seetharaman, J, Su, M, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-10-05 | Release date: | 2012-12-12 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. (CASP Target) TO BE PUBLISHED
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2AJ2
| X-Ray Crystal Structure of Protein VC0467 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR8. | Descriptor: | Hypothetical UPF0301 protein VC0467 | Authors: | Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Kellie, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-08-01 | Release date: | 2005-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | X-Ray structure of hypothetical protein VC0467 from Vibrio cholerae: new fold. Northeast Structural Genomics Consortium target VcR8. To be Published
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2ELA
| Crystal Structure of the PTB domain of human APPL1 | Descriptor: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 | Authors: | Li, J, Mao, X, Dong, L.Q, Liu, F, Tong, L. | Deposit date: | 2007-03-27 | Release date: | 2007-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the BAR-PH and PTB Domains of Human APPL1 Structure, 15, 2007
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