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PDB: 73 件

2Q1E
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Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein.
分子名称: Amyloidogenic immunoglobulin light chain protein AL-09, SULFATE ION
著者Thompson, J.R, Ramirez-Alvarado, M, Baden, E.M.
登録日2007-05-24
公開日2008-04-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Altered dimer interface decreases stability in an amyloidogenic protein.
J.Biol.Chem., 283, 2008
2X3H
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BU of 2x3h by Molmil
COLIPHAGE K5A LYASE
分子名称: BROMIDE ION, K5 LYASE
著者Thompson, J.E, Pourhossein, M, Goldrick, M, Hudson, T, Derrick, J.P, Roberts, I.S.
登録日2010-02-04
公開日2010-06-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The K5 Lyase Kfla Combines a Viral Tail Spike Structure with a Bacterial Polysaccharide Lyase Mechanism.
J.Biol.Chem., 285, 2010
4K07
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Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant
分子名称: Amyloidogenic immunoglobulin light chain protein AL-103, SULFATE ION
著者Thompson, J.R, Berkholz, D.S, Mahlum, E.W, Ramirez-Alvarado, M.
登録日2013-04-03
公開日2013-10-30
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations.
J.Mol.Biol., 426, 2014
1YBA
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The active form of phosphoglycerate dehydrogenase
分子名称: 2-OXOGLUTARIC ACID, D-3-phosphoglycerate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Thompson, J.R, Banaszak, L.J.
登録日2004-12-20
公開日2005-04-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Vmax Regulation through Domain and Subunit Changes. The Active Form of Phosphoglycerate Dehydrogenase
Biochemistry, 44, 2005
1CBI
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APO-CELLULAR RETINOIC ACID BINDING PROTEIN I
分子名称: CELLULAR RETINOIC ACID BINDING PROTEIN I
著者Thompson, J.R, Bratt, J.M, Banaszak, L.J.
登録日1995-07-12
公開日1995-11-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of cellular retinoic acid binding protein I shows increased access to the binding cavity due to formation of an intermolecular beta-sheet.
J.Mol.Biol., 252, 1995
1LSH
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LIPID-PROTEIN INTERACTIONS IN LIPOVITELLIN
分子名称: LIPOVITELLIN (LV-1N, LV-1C), LIPOVITELLIN (LV-2), ...
著者Thompson, J.R, Banaszak, L.J.
登録日2002-05-17
公開日2002-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lipid-protein interactions in lipovitellin.
Biochemistry, 41, 2002
1LFO
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LIVER FATTY ACID BINDING PROTEIN-OLEATE COMPLEX
分子名称: BUTENOIC ACID, LIVER FATTY ACID BINDING PROTEIN, OLEIC ACID, ...
著者Thompson, J, Winter, N, Terwey, D, Bratt, J, Banaszak, L.
登録日1996-12-09
公開日1997-06-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the liver fatty acid-binding protein. A complex with two bound oleates.
J.Biol.Chem., 272, 1997
3DVI
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Crystal structure of kappa 1 amyloidogenic light chain variable domain
分子名称: Amyloidogenic light chain variable domain AL-103
著者Thompson, J.R, Randles, E.G, Ramirez-Alvarado, M.
登録日2008-07-18
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural alterations within native amyloidogenic immunoglobulin light chains.
J.Mol.Biol., 389, 2009
2GGM
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Human centrin 2 xeroderma pigmentosum group C protein complex
分子名称: CALCIUM ION, Centrin-2, DNA-repair protein complementing XP-C cells
著者Thompson, J.R.
登録日2006-03-24
公開日2006-04-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The structure of the human centrin 2-xeroderma pigmentosum group C protein complex.
J.Biol.Chem., 281, 2006
2Q20
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Structure of the germline Vk1 O18/O8 light chain variable domain homodimer
分子名称: Vk1 O18/O8 germline light chain variable domain
著者Thompson, J.R, Ramirez-Alvarado, M, Baden, E.M.
登録日2007-05-25
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Altered dimer interface decreases stability in an amyloidogenic protein.
J.Biol.Chem., 283, 2008
3ZD0
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The Solution Structure of Monomeric Hepatitis C Virus p7 Yields Potent Inhibitors of Virion Release
分子名称: P7 PROTEIN
著者Foster, T.L, Sthompson, G, Kalverda, A.P, Kankanala, J, Thompson, J, Barker, A.M, Clarke, D, Noerenberg, M, Pearson, A.R, Rowlands, D.J, Homans, S.W, Harris, M, Foster, R, Griffin, S.D.C.
登録日2012-11-23
公開日2013-09-04
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus P7 as a Viable Class of Antivirals Targeting Virion Release
Hepatology, 59, 2014
4W8S
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Crystal structure of truncated hemolysin A Q125S/Y134S from P. mirabilis at 1.5 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Crystal structure of truncated hemolysin A Q125S/Y134S from P. mirabilis at 1.5 Angstroms resolution
To Be Published
7RR9
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Cryo-EM Structure of Nanodisc reconstituted ABCD1 in nucleotide bound outward open conformation
分子名称: ATP-binding cassette sub-family D member 1, CHOLESTEROL, MAGNESIUM ION, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2021-08-09
公開日2022-01-19
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Commun Biol, 5, 2022
7RRA
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Cryo-EM Structure of Nanodisc reconstituted ABCD1 in inward open conformation
分子名称: ATP-binding cassette sub-family D member 1
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2021-08-09
公開日2022-01-19
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Commun Biol, 5, 2022
4W8T
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BU of 4w8t by Molmil
Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-10-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.539 Å)
主引用文献Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
To Be Published
2FHD
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Crystal structure of Crb2 tandem tudor domains
分子名称: DNA repair protein rhp9/CRB2, PHOSPHATE ION
著者Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G.
登録日2005-12-23
公開日2007-01-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Cell(Cambridge,Mass.), 127, 2006
2B02
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Crystal Structure of ARNT PAS-B Domain
分子名称: Aryl hydrocarbon receptor nuclear translocator
著者Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G.
登録日2005-09-12
公開日2006-10-24
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
2ETX
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BU of 2etx by Molmil
Crystal Structure of MDC1 Tandem BRCT Domains
分子名称: Mediator of DNA damage checkpoint protein 1
著者Wasielewski, E, Kim, Y, Joachimiak, A, Thompson, J.R, Mer, G.
登録日2005-10-27
公開日2005-11-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex.
J.Biol.Chem., 287, 2012
4W8R
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BU of 4w8r by Molmil
Crystal structure of hemolysin A Y134F from P. mirabilis at 1.5 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-10-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.519 Å)
主引用文献Crystal structure of hemolysin A Y134F from P. mirabilis at 1.5 Angstroms resolution
To Be Published
5KZ5
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BU of 5kz5 by Molmil
Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery: the Complex Formed by the Iron Donor, the Sulfur Donor, and the Scaffold
分子名称: Cysteine desulfurase, mitochondrial, Frataxin, ...
著者Gakh, O, Ranatunga, W, Smith, D.Y, Ahlgren, E.C, Al-Karadaghi, S, Thompson, J.R, Isaya, G.
登録日2016-07-22
公開日2016-08-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (14.3 Å)
主引用文献Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.
J.Biol.Chem., 291, 2016
3V5Z
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Structure of FBXL5 hemerythrin domain, C2 cell, grown anaerobically
分子名称: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
著者Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
登録日2011-12-17
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1847 Å)
主引用文献Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
3V5Y
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Structure of FBXL5 hemerythrin domain, P2(1) cell
分子名称: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
著者Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
登録日2011-12-17
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
3V5X
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Structure of FBXL5 hemerythrin domain, C2 cell
分子名称: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
著者Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
登録日2011-12-17
公開日2012-01-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
1SNK
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BU of 1snk by Molmil
Cathepsin K complexed with carbamate derivatized norleucine aldehyde
分子名称: Cathepsin K, N2-({[(4-BROMOPHENYL)METHYL]OXY}CARBONYL)-N1-[(1S)-1-FORMYLPENTYL]-L-LEUCINAMIDE, SULFATE ION
著者Boros, E.E, Deaton, D.N, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Thompson, J.B, Willard Jr, D.H, Wright, L.L.
登録日2004-03-11
公開日2004-06-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Exploration of the P(2)-P(3) SAR of aldehyde cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
8EEB
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BU of 8eeb by Molmil
Cryo-EM structure of human ABCA7 in Digitonin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023

 

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