5KZ5
Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery: the Complex Formed by the Iron Donor, the Sulfur Donor, and the Scaffold
Summary for 5KZ5
Entry DOI | 10.2210/pdb5kz5/pdb |
EMDB information | 8293 8301 |
Descriptor | Cysteine desulfurase, mitochondrial, Frataxin, mitochondrial, Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (3 entities in total) |
Functional Keywords | frataxin, iron-sulfur protein, mitochondria, protein complex, transferase-oxidoreductase complex, transferase/oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 36 |
Total formula weight | 897651.04 |
Authors | Gakh, O.,Ranatunga, W.,Smith, D.Y.,Ahlgren, E.C.,Al-Karadaghi, S.,Thompson, J.R.,Isaya, G. (deposition date: 2016-07-22, release date: 2016-08-31, Last modification date: 2019-12-18) |
Primary citation | Gakh, O.,Ranatunga, W.,Smith, D.Y.,Ahlgren, E.C.,Al-Karadaghi, S.,Thompson, J.R.,Isaya, G. Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. J.Biol.Chem., 291:21296-21321, 2016 Cited by PubMed: 27519411DOI: 10.1074/jbc.M116.738542 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (14.3 Å) |
Structure validation
Download full validation report