2Q1E
Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein.
Summary for 2Q1E
| Entry DOI | 10.2210/pdb2q1e/pdb |
| Descriptor | Amyloidogenic immunoglobulin light chain protein AL-09, SULFATE ION (3 entities in total) |
| Functional Keywords | al, light chain amyloidosis, amyloid, immunoglobulin, light chain, light chain variable domain, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 47920.65 |
| Authors | Thompson, J.R.,Ramirez-Alvarado, M.,Baden, E.M. (deposition date: 2007-05-24, release date: 2008-04-08, Last modification date: 2024-04-03) |
| Primary citation | Baden, E.M.,Owen, B.A.,Peterson, F.C.,Volkman, B.F.,Ramirez-Alvarado, M.,Thompson, J.R. Altered dimer interface decreases stability in an amyloidogenic protein. J.Biol.Chem., 283:15853-15860, 2008 Cited by PubMed: 18400753DOI: 10.1074/jbc.M705347200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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