3DVI

Crystal structure of kappa 1 amyloidogenic light chain variable domain

Summary for 3DVI

Entry DOI	10.2210/pdb3dvi/pdb
Related	2q1e 2q20
Descriptor	Amyloidogenic light chain variable domain AL-103 (2 entities in total)
Functional Keywords	al, light chain amyloidosis, amyloid, immunoglobulin, light chain, light chain variable domain, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	11972.26
Authors	Thompson, J.R.,Randles, E.G.,Ramirez-Alvarado, M. (deposition date: 2008-07-18, release date: 2009-05-12, Last modification date: 2023-08-30)
Primary citation	Randles, E.G.,Thompson, J.R.,Martin, D.J.,Ramirez-Alvarado, M. Structural alterations within native amyloidogenic immunoglobulin light chains. J.Mol.Biol., 389:199-210, 2009 Cited by PubMed: 19361523 DOI: 10.1016/j.jmb.2009.04.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation