2ETX

Crystal Structure of MDC1 Tandem BRCT Domains

Summary for 2ETX

Entry DOI	10.2210/pdb2etx/pdb
Descriptor	Mediator of DNA damage checkpoint protein 1 (2 entities in total)
Functional Keywords	tandem brct domains histone gamma-h2ax, cell cycle
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q14676
Total number of polymer chains	2
Total formula weight	45826.96
Authors	Wasielewski, E.,Kim, Y.,Joachimiak, A.,Thompson, J.R.,Mer, G. (deposition date: 2005-10-27, release date: 2005-11-15, Last modification date: 2024-02-14)
Primary citation	Singh, N.,Wiltshire, T.D.,Thompson, J.R.,Mer, G.,Couch, F.J. Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. J.Biol.Chem., 287:2854-2862, 2012 Cited by PubMed: 22139841 DOI: 10.1074/jbc.M111.307868 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.33 Å)

Structure validation