4V7H
 
 | | Structure of the 80S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution | | 分子名称: | 18S rRNA, 26S ribosomal RNA, 40S ribosomal protein S0(A), ... | | 著者 | Taylor, D.J, Devkota, B, Huang, A.D, Topf, M, Narayanan, E, Sali, A, Harvey, S.C, Frank, J. | | 登録日 | 2009-09-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Comprehensive molecular structure of the eukaryotic ribosome.
Structure, 17, 2009
|
|
2P8Z
 | | Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ... | | 著者 | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | | 登録日 | 2007-03-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
|
|
2P8W
 | | Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction | | 分子名称: | Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | | 登録日 | 2007-03-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (11.3 Å) | | 主引用文献 | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
|
|
2P8X
 | | Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP cryo-EM reconstruction | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ... | | 著者 | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | | 登録日 | 2007-03-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | | 主引用文献 | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
|
|
2P8Y
 | | Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDP:sordarin cryo-EM reconstruction | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | | 登録日 | 2007-03-23 | | 公開日 | 2007-05-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | | 主引用文献 | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
|
|
8FZR
 | |
2QQP
 | |
8TZV
 | | Apo form of human ATE1 | | 分子名称: | Isoform ATE1-2 of Arginyl-tRNA--protein transferase 1, ZINC ION | | 著者 | Huang, W, Zhang, Y, Taylor, D.J. | | 登録日 | 2023-08-28 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Nat Commun, 15, 2024
|
|
8UAU
 | | human ATE1 in complex with Arg-tRNA and a peptide substrate | | 分子名称: | Isoform ATE1-2 of Arginyl-tRNA--protein transferase 1, RNA (76-MER), ZINC ION, ... | | 著者 | Huang, W, Zhang, Y, Taylor, D.J. | | 登録日 | 2023-09-22 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Nat Commun, 15, 2024
|
|
7UO0
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ... | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
|
|
7UO1
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ... | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
|
|
7UO2
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
|
|
7UO5
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, RNase P RNA, Ribonuclease P protein component | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
|
|
3S6P
 | |
8E3S
 | |
7MEJ
 | |
7MDW
 | |
7ME7
 | |
6E53
 | | Structure of TERT in complex with a novel telomerase inhibitor | | 分子名称: | MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ... | | 著者 | Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J. | | 登録日 | 2018-07-19 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019
|
|
8CVN
 | | Cryo-EM Structure of Human 15-PGDH in Complex with Small Molecule SW209415 | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-[butyl(oxidanyl)-$l^{3}-sulfanyl]-4-(2,3-dimethylimidazol-4-yl)-6-(1,3-thiazol-2-yl)thieno[2,3-b]pyridin-3-amine | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system.
Nat Commun, 14, 2023
|
|
8CWL
 | |
