7MDW

CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb105

Summary for 7MDW

• Entry DOI: 10.2210/pdb7mdw/pdb
• EMDB information: 23782
• Descriptor: nonobody Nb21, Spike protein S1, nanobody Nb105, ... (4 entities in total)
• Functional Keywords: sars-cov-2 receptor binding domain nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lama glama (Llama); More
• Total number of polymer chains: 3
• Total formula weight: 48385.91

Authors

Huang, W.,Taylor, D.J. (deposition date: 2021-04-06, release date: 2021-08-11)

• Primary citation: Sun, D.,Sang, Z.,Kim, Y.J.,Xiang, Y.,Cohen, T.,Belford, A.K.,Huet, A.,Conway, J.F.,Sun, J.,Taylor, D.J.,Schneidman-Duhovny, D.,Zhang, C.,Huang, W.,Shi, Y.; Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes; Nat Commun, 12:4676-, 2021; DOI: 10.1038/s41467-021-24963-3

Experimental method

ELECTRON MICROSCOPY (3.58 Å)