6M7L
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![BU of 6m7l by Molmil](/molmil-images/mine/6m7l) | Complex of OxyA with the X-domain from GPA biosynthesis | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase, Putative non-ribosomal peptide synthetase | Authors: | Greule, A, Izore, T, Tailhades, J, Peschke, M, Schoppet, M, Ahmed, I, Kulik, A, Adamek, M, Ziemert, N, De Voss, J, Stegmann, E, Cryle, M.J. | Deposit date: | 2018-08-20 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.648297 Å) | Cite: | Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nat Commun, 10, 2019
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6DYS
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![BU of 6dys by Molmil](/molmil-images/mine/6dys) | C-terminal condensation domain of Ebony in complex with beta-alanyl-dopamine | Descriptor: | CALCIUM ION, Ebony, N-[2-(3,4-dihydroxyphenyl)ethyl]-beta-alaninamide | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6DYN
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![BU of 6dyn by Molmil](/molmil-images/mine/6dyn) | C-terminal condensation domain of Ebony in complex with Histamine | Descriptor: | CALCIUM ION, Ebony, HISTAMINE | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6DYO
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![BU of 6dyo by Molmil](/molmil-images/mine/6dyo) | C-terminal condensation domain of Ebony in complex with L-Dopamine | Descriptor: | CALCIUM ION, Ebony, L-DOPAMINE | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6DYM
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![BU of 6dym by Molmil](/molmil-images/mine/6dym) | C-terminal condensation domain of Ebony | Descriptor: | CALCIUM ION, Ebony | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6DYR
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![BU of 6dyr by Molmil](/molmil-images/mine/6dyr) | C-terminal condensation domain of Ebony in complex with Carcinine | Descriptor: | Ebony, N-[2-(1H-imidazol-5-yl)ethyl]-beta-alaninamide | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1N18
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![BU of 1n18 by Molmil](/molmil-images/mine/1n18) | Thermostable mutant of Human Superoxide Dismutase, C6A, C111S | Descriptor: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | Authors: | Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A. | Deposit date: | 2002-10-16 | Release date: | 2002-11-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase. J.Mol.Biol., 324, 2002
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1N0N
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![BU of 1n0n by Molmil](/molmil-images/mine/1n0n) | Catalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase | Descriptor: | MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] | Authors: | Borgstahl, G.E.O, Parge, H.E, Hickey, M.J, Beyer Jr, W.F, Hallewell, R.A, Tainer, J.A. | Deposit date: | 2002-10-14 | Release date: | 2002-11-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Catalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase to be published
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1N19
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![BU of 1n19 by Molmil](/molmil-images/mine/1n19) | Structure of the HSOD A4V mutant | Descriptor: | COPPER (I) ION, SULFATE ION, Superoxide Dismutase [Cu-Zn], ... | Authors: | Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A. | Deposit date: | 2002-10-16 | Release date: | 2002-11-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase. J.Mol.Biol., 324, 2002
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1MUY
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![BU of 1muy by Molmil](/molmil-images/mine/1muy) | CATALYTIC DOMAIN OF MUTY FROM ESCHERICHIA COLI | Descriptor: | ADENINE GLYCOSYLASE, GLYCEROL, IMIDAZOLE, ... | Authors: | Guan, Y, Tainer, J.A. | Deposit date: | 1998-08-20 | Release date: | 1999-08-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nat.Struct.Biol., 5, 1998
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1MUD
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![BU of 1mud by Molmil](/molmil-images/mine/1mud) | CATALYTIC DOMAIN OF MUTY FROM ESCHERICHIA COLI, D138N MUTANT COMPLEXED TO ADENINE | Descriptor: | ADENINE, Adenine DNA glycosylase, GLYCEROL, ... | Authors: | Guan, Y, Tainer, J.A. | Deposit date: | 1998-08-20 | Release date: | 1999-09-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nat.Struct.Biol., 5, 1998
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1N0J
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![BU of 1n0j by Molmil](/molmil-images/mine/1n0j) | |
2K9N
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![BU of 2k9n by Molmil](/molmil-images/mine/2k9n) | Solution NMR structure of the R2R3 DNA binding domain of Myb1 protein from protozoan parasite Trichomonas vaginalis | Descriptor: | MYB24 | Authors: | Lou, Y, Wei, S, Rajasekaran, M, Chou, C, Hsu, H, Tai, J, Chen, C. | Deposit date: | 2008-10-19 | Release date: | 2009-03-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 37, 2009
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2H3I
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![BU of 2h3i by Molmil](/molmil-images/mine/2h3i) | Solution structure of the HIV-1 myristoylated Matrix protein | Descriptor: | Gag polyprotein, MYRISTIC ACID | Authors: | Saad, J.S, Miller, J, Tai, J, Kim, A, Ghanam, R.H, Summers, M.F. | Deposit date: | 2006-05-22 | Release date: | 2006-07-25 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H3F
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![BU of 2h3f by Molmil](/molmil-images/mine/2h3f) | Solution structure of the HIV-1 MA protein | Descriptor: | Gag polyprotein | Authors: | Saad, J.S, Miller, J, Tai, J, Kim, A, Ghanam, R.H, Summers, M.F. | Deposit date: | 2006-05-22 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H3Z
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![BU of 2h3z by Molmil](/molmil-images/mine/2h3z) | Structure of the HIV-1 matrix protein bound to di-C4-phosphatidylinositol-(4,5)-bisphosphate | Descriptor: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, Gag polyprotein | Authors: | Saad, J.S, Miller, J, Tai, J, Kim, A, Ghanam, R.H, Summers, M.F. | Deposit date: | 2006-05-23 | Release date: | 2006-07-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H3V
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![BU of 2h3v by Molmil](/molmil-images/mine/2h3v) | Structure of the HIV-1 Matrix protein bound to di-C8-phosphatidylinositol-(4,5)-bisphosphate | Descriptor: | Gag polyprotein, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Saad, J.S, Miller, J, Tai, J, Kim, A, Ghanam, R.H, Summers, M.F. | Deposit date: | 2006-05-23 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2JMG
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![BU of 2jmg by Molmil](/molmil-images/mine/2jmg) | Solution structure of V7R mutant of HIV-1 myristoylated matrix protein | Descriptor: | Gag polyprotein, MYRISTIC ACID | Authors: | Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F. | Deposit date: | 2006-11-11 | Release date: | 2007-02-06 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Point mutations in the HIV-1 matrix protein turn off the myristyl switch. J.Mol.Biol., 366, 2007
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2KDZ
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![BU of 2kdz by Molmil](/molmil-images/mine/2kdz) | Structure of the R2R3 DNA binding domain of MYB1 protein from protozoan parasite trichomonas vaginalis in complex with MRE-1/MRE-2R DNA | Descriptor: | 5'-D(*AP*AP*GP*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*TP*A)-3', 5'-D(*TP*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*TP*CP*TP*T)-3', MYB24 | Authors: | Lou, Y.C, Wei, S.Y, Rajasekaran, M, Chou, C.C, Hsu, H.M, Tai, J.H, Chen, C. | Deposit date: | 2009-01-21 | Release date: | 2009-03-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 2009
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7Z3C
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![BU of 7z3c by Molmil](/molmil-images/mine/7z3c) | A novel molecular switch controls assembly of bacterial focal adhesions in response to changes in surface structure. | Descriptor: | Adventurous gliding motility protein GltJ | Authors: | Attia, B, My, L, Castaing, J.P, Le Guenno, H, Espinosa, L, Schmidt, V, Nouailler, M, Bornet, O, Elantak, L, Mignot, T. | Deposit date: | 2022-03-02 | Release date: | 2023-02-22 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A novel molecular switch controls assembly of bacterial focal adhesions To Be Published
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7Z5I
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![BU of 7z5i by Molmil](/molmil-images/mine/7z5i) | Transcription factor MYF5 bound to symmetrical site | Descriptor: | DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3'), Myogenic factor 5 | Authors: | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | Deposit date: | 2022-03-09 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Transcription factor MYF5 bound to symmetrical site To Be Published
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7Z5K
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![BU of 7z5k by Molmil](/molmil-images/mine/7z5k) | |
8TLY
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![BU of 8tly by Molmil](/molmil-images/mine/8tly) | |
8TUK
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![BU of 8tuk by Molmil](/molmil-images/mine/8tuk) | Alvinella ASCC1 KH and Phosphodiesterase/Ligase Domain | Descriptor: | 1,2-ETHANEDIOL, Activating signal cointegrator 1 complex subunit 1, IMIDAZOLE | Authors: | Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Chinnam, N.B. | Deposit date: | 2023-08-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase. J.Biol.Chem., 300, 2024
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6VBA
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![BU of 6vba by Molmil](/molmil-images/mine/6vba) | Structure of human Uracil DNA Glycosylase (UDG) bound to Aurintricarboxylic acid (ATA) | Descriptor: | 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid), Uracil-DNA glycosylase | Authors: | Moiani, D, Arvai, A.S, Tainer, J.A. | Deposit date: | 2019-12-18 | Release date: | 2021-03-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Prog.Biophys.Mol.Biol., 163, 2021
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