6VBA
Structure of human Uracil DNA Glycosylase (UDG) bound to Aurintricarboxylic acid (ATA)
Summary for 6VBA
Entry DOI | 10.2210/pdb6vba/pdb |
Related | 1AKZ |
Descriptor | Uracil-DNA glycosylase, 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid) (3 entities in total) |
Functional Keywords | glycosylase, dna repair, uracil removal from dna, alpha/ beta protein, glycosidase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 25966.48 |
Authors | Moiani, D.,Arvai, A.S.,Tainer, J.A. (deposition date: 2019-12-18, release date: 2021-03-03, Last modification date: 2023-10-11) |
Primary citation | Nguyen, M.T.,Moiani, D.,Ahmed, Z.,Arvai, A.S.,Namjoshi, S.,Shin, D.S.,Fedorov, Y.,Selvik, E.J.,Jones, D.E.,Pink, J.,Yan, Y.,Laverty, D.J.,Nagel, Z.D.,Tainer, J.A.,Gerson, S.L. An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Prog.Biophys.Mol.Biol., 163:143-159, 2021 Cited by PubMed: 33675849DOI: 10.1016/j.pbiomolbio.2021.02.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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