8SDC
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![BU of 8sdc by Molmil](/molmil-images/mine/8sdc) | Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | 分子名称: | Alpha/beta hydrolase fold protein, CHLORIDE ION | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | 登録日 | 2023-04-06 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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8SDD
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![BU of 8sdd by Molmil](/molmil-images/mine/8sdd) | Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate | 分子名称: | Alpha/beta hydrolase fold protein | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | 登録日 | 2023-04-06 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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4Q3K
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![BU of 4q3k by Molmil](/molmil-images/mine/4q3k) | Crystal structure of MGS-M1, an alpha/beta hydrolase enzyme from a Medee basin deep-sea metagenome library | 分子名称: | CHLORIDE ION, FLUORIDE ION, MGS-M1, ... | 著者 | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2014-04-11 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4Q3L
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![BU of 4q3l by Molmil](/molmil-images/mine/4q3l) | Crystal structure of MGS-M2, an alpha/beta hydrolase enzyme from a Medee basin deep-sea metagenome library | 分子名称: | GLYCEROL, MGS-M2 | 著者 | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2014-04-11 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4QL5
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![BU of 4ql5 by Molmil](/molmil-images/mine/4ql5) | Crystal structure of translation initiation factor IF-1 from Streptococcus pneumoniae TIGR4 | 分子名称: | ACETATE ION, GLYCEROL, Translation initiation factor IF-1, ... | 著者 | Stogios, P.J, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-06-10 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.025 Å) | 主引用文献 | Crystal structure of translation initiation factor IF-1 from Streptococcus pneumoniae TIGR4 TO BE PUBLISHED
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4Q3N
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![BU of 4q3n by Molmil](/molmil-images/mine/4q3n) | Crystal structure of MGS-M5, a lactate dehydrogenase enzyme from a Medee basin deep-sea metagenome library | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2014-04-11 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4Q3O
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![BU of 4q3o by Molmil](/molmil-images/mine/4q3o) | Crystal structure of MGS-MT1, an alpha/beta hydrolase enzyme from a Lake Matapan deep-sea metagenome library | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2014-04-11 | 公開日 | 2015-03-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
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4R01
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![BU of 4r01 by Molmil](/molmil-images/mine/4r01) | Crystal structure of SP1627, a putative NADH-flavin reductase, from Streptococcus pneumoniae TIGR4 | 分子名称: | CHLORIDE ION, SULFATE ION, putative NADH-flavin reductase | 著者 | Stogios, P.J, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-07-29 | 公開日 | 2014-08-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of SP1627, a putative NADH-flavin reductase, from Streptococcus pneumoniae TIGR4 TO BE PUBLISHED
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6O62
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![BU of 6o62 by Molmil](/molmil-images/mine/6o62) | Crystal structure of Sec4p, a Rab family GTPase from Candida albicans | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein SEC4 | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-03-05 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | To be published To Be Published
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6P2K
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![BU of 6p2k by Molmil](/molmil-images/mine/6p2k) | Crystal structure of AFV00434, an ancestral GH74 enzyme | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Stogios, P.J, Skarina, T, Arnal, G, Brumer, H, Savchenko, A. | 登録日 | 2019-05-21 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
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6P2M
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![BU of 6p2m by Molmil](/molmil-images/mine/6p2m) | Crystal structure of the Caldicellulosiruptor lactoaceticus GH74 (ClGH74a) enzyme in complex with LLG xyloglucan | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, GLYCEROL, ... | 著者 | Stogios, P.J, Skarina, T, Arnal, G. | 登録日 | 2019-05-21 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
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6P2O
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![BU of 6p2o by Molmil](/molmil-images/mine/6p2o) | Crystal structure of Streptomyces rapamycinicus GH74 in complex with xyloglucan fragments XLLG and XXXG | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Stogios, P.J, Skarina, T, Arnal, G, Brumer, H, Savchenko, A. | 登録日 | 2019-05-21 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
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6PI9
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![BU of 6pi9 by Molmil](/molmil-images/mine/6pi9) | Crystal structure of 16S rRNA methyltransferase RmtF in complex with S-Adenosyl-L-homocysteine | 分子名称: | 16S rRNA (guanine(1405)-N(7))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Stogios, P.J, Kim, Y, Evdokimova, E, Di Leo, R, Semper, C, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-06-26 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of 16S rRNA methylase RmtF in complex with S-Adenosyl-L-homocysteine To be Published
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6P2L
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![BU of 6p2l by Molmil](/molmil-images/mine/6p2l) | Crystal structure of Niastella koreensis GH74 (NkGH74) enzyme | 分子名称: | CHLORIDE ION, Glycosyl hydrolase BNR repeat-containing protein, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Stogios, P.J, Skarina, T, Arnal, G, Brumer, H, Savchenko, A. | 登録日 | 2019-05-21 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
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6P2N
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![BU of 6p2n by Molmil](/molmil-images/mine/6p2n) | |
6PTA
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![BU of 6pta by Molmil](/molmil-images/mine/6pta) | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP | 分子名称: | ADP-ribosylation factor, GUANOSINE-5'-DIPHOSPHATE | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-07-15 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP To Be Published
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8D5H
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![BU of 8d5h by Molmil](/molmil-images/mine/8d5h) | Crystal structure of dihydropteroate synthase (folP-SMZ_B27) from soil uncultured bacterium in complex with 6-hydroxymethyl-7,8-dihydropterin | 分子名称: | 6-HYDROXYMETHYLPTERIN, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Stogios, P.J, Skarina, T, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-06-04 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of dihydropteroate synthase (folP-SMZ_B27) from soil uncultured bacterium in complex with 6-hydroxymethyl-7,8-dihydropterin To Be Published
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8D5I
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![BU of 8d5i by Molmil](/molmil-images/mine/8d5i) | Crystal structure of dihydropteroate synthase H182G mutant (folP-SMZ_B27) from soil uncultured bacterium in complex with pteroic acid and pyrophosphate | 分子名称: | PTEROIC ACID, PYROPHOSPHATE 2-, folP-SMZ_B27 | 著者 | Stogios, P.J, Skarina, T, Kim, Y, Di Leo, R, Venkatesan, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-06-04 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of dihydropteroate synthase H182G mutant (folP-SMZ_B27) from soil uncultured bacterium in complex with pteroic acid To Be Published
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8D5G
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![BU of 8d5g by Molmil](/molmil-images/mine/8d5g) | Crystal structure of dihydropteroate synthase (folP-SMZ_B27) from soil uncultured bacterium in complex with 6-hydroxymethyl-7,8-dihydropterin pyrophosphate | 分子名称: | 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, CHLORIDE ION, folP-SMZ_B27 | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-06-04 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Crystal structure of dihydropteroate synthase (folP-SMZ_B27) from soil uncultured bacterium in complex with 6-hydroxymethyl-7,8-dihydropterin pyrophosphate To Be Published
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6M8T
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![BU of 6m8t by Molmil](/molmil-images/mine/6m8t) | Crystal structure of UbiX-like FMN prenyltransferase AF1214 from Archaeoglobus fulgidus, FMN complex | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavin prenyltransferase UbiX, PHOSPHATE ION | 著者 | Stogios, P.J, Skarina, T, Khusnutidnova, A, Wawrzak, Z, Yakunin, A.F, Savchenko, A. | 登録日 | 2018-08-22 | 公開日 | 2020-02-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Crystal structure of UbiX-like FMN prenyltransferase AF1214 from Archaeoglobus fulgidus, FMN complex To Be Published
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6MN5
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![BU of 6mn5 by Molmil](/molmil-images/mine/6mn5) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with gentamicin C1A | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | Stogios, P.J, Evdokimova, E, Kim, Y, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-10-01 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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6MMZ
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![BU of 6mmz by Molmil](/molmil-images/mine/6mmz) | Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, H29A mutant apoenzyme | 分子名称: | Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, SULFATE ION | 著者 | Stogios, P.J, Skarina, T, Xu, Z, Yim, V, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-10-01 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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6MGL
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![BU of 6mgl by Molmil](/molmil-images/mine/6mgl) | Crystal structure of the catalytic domain from GH74 enzyme PoGH74 from Paenibacillus odorifer, D60A mutant in complex with XXLG and XGXXLG xyloglucan | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Stogios, P.J, Skarina, T, Arnal, G, Watanabe, N, Brumer, H, Savchenko, A. | 登録日 | 2018-09-14 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74endo-xyloglucanase. Biochem. J., 475, 2018
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6MGJ
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![BU of 6mgj by Molmil](/molmil-images/mine/6mgj) | Crystal structure of the catalytic domain from GH74 enzyme PoGH74 from Paenibacillus odorifer, apoenzyme | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Stogios, P.J, Skarina, T, Nocek, B, Arnal, G, Brumer, H, Savchenko, A. | 登録日 | 2018-09-14 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74endo-xyloglucanase. Biochem. J., 475, 2018
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6MN4
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![BU of 6mn4 by Molmil](/molmil-images/mine/6mn4) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with apramycin | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, APRAMYCIN, ... | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-10-01 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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