6MMZ
Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, H29A mutant apoenzyme
Summary for 6MMZ
Entry DOI | 10.2210/pdb6mmz/pdb |
Related | 5HT0 |
Descriptor | Aminoglycoside N(3)-acetyltransferase, SULFATE ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | antibiotic_nat family, acetyltransferase, aminoglycoside, antibiotic resistance, metagenome, soil, coenzyme a, csgid, transferase, center for structural genomics of infectious diseases, national institute of allergy and infectious diseases, niaid |
Biological source | uncultured bacterium |
Total number of polymer chains | 6 |
Total formula weight | 175396.03 |
Authors | Stogios, P.J.,Skarina, T.,Xu, Z.,Yim, V.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-10-01, release date: 2018-10-24, Last modification date: 2023-11-15) |
Primary citation | Stogios, P.J.,Bordeleau, E.,Xu, Z.,Skarina, T.,Evdokimova, E.,Chou, S.,Diorio-Toth, L.,D'Souza, A.W.,Patel, S.,Dantas, G.,Wright, G.D.,Savchenko, A. Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5:263-263, 2022 Cited by PubMed: 35338238DOI: 10.1038/s42003-022-03219-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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