8SDD

Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate

Summary for 8SDD

• Entry DOI: 10.2210/pdb8sdd/pdb
• Related: 8SDC
• Descriptor: Alpha/beta hydrolase fold protein (2 entities in total)
• Functional Keywords: fluoroacetate, dehalogenase, hydrolase, alpha/beta hydrolase
• Biological source: Dechloromonas aromatica RCB
• Total number of polymer chains: 2
• Total formula weight: 66139.04

Authors

Stogios, P.J.,Skarina, T.,Khusnutdinova, A.,Iakounine, A.,Savchenko, A. (deposition date: 2023-04-06, release date: 2024-02-14)

• Primary citation: Khusnutdinova, A.N.,Batyrova, K.A.,Brown, G.,Fedorchuk, T.,Chai, Y.S.,Skarina, T.,Flick, R.,Petit, A.P.,Savchenko, A.,Stogios, P.,Yakunin, A.F.; Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.; Febs J., 290:4966-4983, 2023; PubMed: 37437000; DOI: 10.1111/febs.16903

Experimental method

X-RAY DIFFRACTION (2 Å)