4LTC
 
 | | Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6 | | 分子名称: | N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ... | | 著者 | Stein, M, Trivella, D.B.B, Groll, M. | | 登録日 | 2013-07-23 | | 公開日 | 2014-07-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
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4FZG
 | | 20S yeast proteasome in complex with glidobactin | | 分子名称: | Glidobactin, Proteasome component C1, Proteasome component C11, ... | | 著者 | Stein, M, Beck, P, Kaiser, M, Dudler, R, Becker, C.F.W, Groll, M. | | 登録日 | 2012-07-06 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FZC
 | | 20S yeast proteasome in complex with cepafungin I | | 分子名称: | Cepafungin I, Proteasome component C1, Proteasome component C11, ... | | 著者 | Stein, M, Beck, P, Kaiser, M, Dudler, R, Becker, C.F.W, Groll, M. | | 登録日 | 2012-07-06 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor.
Proc.Natl.Acad.Sci.USA, 109, 2012
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8PKE
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8PKG
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8PKF
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287D
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188D
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3FCD
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2D95
 | | LOW-TEMPERATURE STUDY OF THE A-DNA FRAGMENT D(GGGCGCCC) | | 分子名称: | DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*C)-3') | | 著者 | Eisenstein, M, Hope, H, Haran, T.E, Frolow, F, Shakked, Z, Rabinovich, D. | | 登録日 | 1993-07-13 | | 公開日 | 1994-01-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Low-temperature study of the A-DNA fragment d(GGGCGCCC)
ACTA CRYSTALLOGR.,SECT.B, 44, 1988
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1VT9
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1VTA
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187D
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189D
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8D3A
 | | Crystal Structure of DH475 Fab in complex with Man9 | | 分子名称: | DH475 Fab heavy chain, DH475 Fab light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Finkelstein, M, Fera, D. | | 登録日 | 2022-06-01 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage.
Front Immunol, 13, 2022
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1TOF
 | | THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES | | 分子名称: | THIOREDOXIN H | | 著者 | Mittard, V, Blackledge, M.J, Stein, M, Jacquot, J.-P, Marion, D, Lancelin, J.-M. | | 登録日 | 1996-05-30 | | 公開日 | 1996-12-07 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii.
Eur.J.Biochem., 243, 1997
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3CWX
 | | Crystal structure of cagd from helicobacter pylori pathogenicity island | | 分子名称: | protein CagD | | 著者 | Cendron, L, Zanotti, G, Angelini, A, Barison, N, Couturier, M, Stein, M. | | 登録日 | 2008-04-23 | | 公開日 | 2008-12-30 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
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3CWY
 | | Structure of CagD from H. pylori pathogenicity island crystallized in the presence of Cu(II) ions | | 分子名称: | COPPER (II) ION, protein CagD | | 著者 | Cendron, L, Zanotti, G, Angelini, A, Barison, N, Couturier, M, Stein, M. | | 登録日 | 2008-04-23 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
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4HNP
 | | Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin analogue VNK1 | | 分子名称: | N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylhept-1-en-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, ... | | 著者 | Trivella, D.B.B, Stein, M, Groll, M. | | 登録日 | 2012-10-20 | | 公開日 | 2014-01-29 | | 最終更新日 | 2014-07-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
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4HRC
 | | Crystal structure of yeast 20S proteasome in complex with epoxyketone carmaphycin analogue 3 | | 分子名称: | N-hexanoyl-L-valyl-N~1~-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, Proteasome component C11, ... | | 著者 | Trivella, D.B.B, Stein, M, Groll, M. | | 登録日 | 2012-10-27 | | 公開日 | 2014-01-29 | | 最終更新日 | 2014-07-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
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4HRD
 | | Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A | | 分子名称: | N-[(2S)-1-({(2S)-1-{[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]amino}-4-[(R)-methylsulfinyl]-1-oxobutan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]hexanamide, Proteasome component C1, Proteasome component C11, ... | | 著者 | Trivella, D.B.B, Stein, M, Groll, M. | | 登録日 | 2012-10-27 | | 公開日 | 2014-01-29 | | 最終更新日 | 2014-07-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
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3OKJ
 | | Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition | | 分子名称: | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)-4-oxobutan-2-yl]-L-leucinamide, Proteasome component C1, Proteasome component C11, ... | | 著者 | Groll, M, Poynor, M, Gallastegui, P, Stein, M, Schmidt, B, Kloetzel, P.M, Huber, R. | | 登録日 | 2010-08-25 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition
Angew.Chem.Int.Ed.Engl., 50, 2011
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4R02
 | | yCP in complex with BSc4999 (alpha-Keto Phenylamide) | | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-{(2S,3S)-1-[(2,4-dimethylphenyl)amino]-2-hydroxy-5-methyl-1-oxohexan-3-yl}-L-leucinamide, Probable proteasome subunit alpha type-7, ... | | 著者 | Voss, C, Scholz, C, Knorr, S, Beck, P, Stein, M, Zall, A, Kuckelkorn, U, Kloetzel, P.-M, Groll, M, Hamacher, K, Schmidt, B. | | 登録日 | 2014-07-29 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | alpha-Keto Phenylamides as P1'-Extended Proteasome Inhibitors.
Chemmedchem, 9, 2014
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2UZ5
 | | Solution structure of the fkbp-domain of Legionella pneumophila Mip | | 分子名称: | MACROPHAGE INFECTIVITY POTENTIATOR | | 著者 | Ceymann, A, Horstmann, M, Ehses, P, Schweimer, K, Steinert, M, Kamphausen, T, Fischer, G, Hacker, J, Rosch, P, Faber, C. | | 登録日 | 2007-04-25 | | 公開日 | 2007-06-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Domain Motions of the Mip Protein from Legionella Pneumophila
Biochemistry, 45, 2006
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7B9E
 | | Crystal structure of MurE from E.coli in complex with Z275151340 | | 分子名称: | 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide, ISOPROPYL ALCOHOL, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase | | 著者 | Koekemoer, L, Steindel, M, Fairhead, M, Talon, R, Douangamath, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Krojer, T, Structural Genomics Consortium (SGC) | | 登録日 | 2020-12-14 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Crystal structure of MurE from E.coli
To Be Published
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