4FZG
20S yeast proteasome in complex with glidobactin
Summary for 4FZG
| Entry DOI | 10.2210/pdb4fzg/pdb |
| Related | 1RYP 2CZY 3BDM 4FZC |
| Related PRD ID | PRD_001016 |
| Descriptor | Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total) |
| Functional Keywords | ubiquitin, proteasome, drug development, inhibitor, natural product, n-terminal nucleophilic hydrolase, protein degradation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
| Total number of polymer chains | 32 |
| Total formula weight | 706369.01 |
| Authors | Stein, M.,Beck, P.,Kaiser, M.,Dudler, R.,Becker, C.F.W.,Groll, M. (deposition date: 2012-07-06, release date: 2012-10-24, Last modification date: 2023-11-15) |
| Primary citation | Stein, M.L.,Beck, P.,Kaiser, M.,Dudler, R.,Becker, C.F.,Groll, M. One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor. Proc.Natl.Acad.Sci.USA, 109:18367-18371, 2012 Cited by PubMed: 23091006DOI: 10.1073/pnas.1211423109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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