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PDB: 453 件
2I59
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Solution structure of RGS10
分子名称: Regulator of G-protein signaling 10
著者Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2006-08-24
公開日2006-10-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2IHB
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Crystal structure of the heterodimeric complex of human RGS10 and activated Gi alpha 3
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, MAGNESIUM ION, ...
著者Soundararajan, M, Turnbull, A.P, Papagrigoriou, E, Pike, A.C.W, Bunkoczi, G, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2006-09-26
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6B3N
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Solution structure of the N-terminal domain of the effector NleG5-1 from Escherichia coli O157:H7 str. Sakai
分子名称: NleG5-1
著者Valleau, D, Houliston, S, Lemak, A, Anderson, W.F, Arrowsmith, C, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-09-22
公開日2017-11-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of the effector NleG5-1 from Escherichia coli O157:H7 str. Sakai
To Be Published
2W2I
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Crystal structure of the human 2-oxoglutarate oxygenase LOC390245
分子名称: 2-OXOGLUTARATE OXYGENASE, GLYCEROL, NICKEL (II) ION, ...
著者Yue, W.W, Ng, S, Shafqat, N, Ugochukwu, E, McDonough, M, Pike, A.C.W, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C, Oppermann, U.
登録日2008-10-31
公開日2009-01-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family.
J.Biol.Chem., 286, 2011
2IK8
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Crystal structure of the heterodimeric complex of human RGS16 and activated Gi alpha 1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Soundararajan, M, Turnbull, A.P, Papagrigoriou, E, Debreczeni, J, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2006-10-02
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2GDZ
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Crystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+
分子名称: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Pilka, E.S, Guo, K, Kavanagh, K, Von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-03-17
公開日2006-04-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-Affinity Inhibitors of Human NAD-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships.
Plos One, 5, 2010
2GTP
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Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2006-04-28
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2WWU
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Crystal structure of the catalytic domain of PHD finger protein 8
分子名称: ACETATE ION, NICKEL (II) ION, PHD FINGER PROTEIN 8, ...
著者Yue, W.W, Hozjan, V, Cooper, C, Tumber, A, Krojer, T, Muniz, J, Allerston, C, Salah, E, McDonough, M.A, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C.J, Kavanagh, K.L, Oppermann, U.
登録日2009-10-29
公開日2009-11-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
FEBS Lett., 584, 2010
2J67
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The TIR domain of human Toll-Like Receptor 10 (TLR10)
分子名称: TOLL LIKE RECEPTOR 10
著者Stenmark, P, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-09-26
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283, 2008
2JAK
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Human PP2A regulatory subunit B56g
分子名称: SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM
著者Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Lundgren, S, Moche, M, Nilsson, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
登録日2006-11-29
公開日2006-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of the Pp2A Regulatory Subunit B56 Gamma: The Remaining Piece of the Pp2A Jigsaw Puzzle.
Proteins, 74, 2009
2JKU
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Crystal structure of the N-terminal region of the biotin acceptor domain of human propionyl-CoA carboxylase
分子名称: PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL, TETRAETHYLENE GLYCOL
著者Healy, S, Yue, W.W, Kochan, G, Pilka, E.S, Murray, J.W, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Wikstrom, M, Edwards, A, Bountra, C, Gravel, R.A, Oppermann, U.
登録日2008-08-30
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment.
Biochemistry, 49, 2010
2J2C
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Crystal structure of Human Cytosolic 5'-Nucleotidase II (NT5C2, cN-II)
分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ...
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Karlberg, T, Kotenyova, T, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-08-16
公開日2006-09-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2J8Q
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Crystal structure of human cleavage and polyadenylation specificity factor 5 (CPSF5) in complex with a sulphate ion.
分子名称: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5, SULFATE ION
著者Moche, M, Stenmark, P, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg, S.L, Hogbom, M, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-10-27
公開日2006-11-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of Human Cleavage and Polyadenylation Specific Factor-5 Reveals a Dimeric Nudix Protein with a Conserved Catalytic Site.
Proteins, 73, 2008
2HE3
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Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
分子名称: CHLORIDE ION, Glutathione peroxidase 2
著者Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-06-21
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
2J4E
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THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
分子名称: INOSINE 5'-TRIPHOSPHATE, INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINIC ACID, ...
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmbergschiavone, L, Hogbom, M, Kotenyova, T, Landry, R, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Schuler, H, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-08-29
公開日2006-09-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
2JGA
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Crystal structure of human cytosolic 5'-nucleotidase III in complex with phosphate and magnesium
分子名称: CYTOSOLIC 5'-NUCLEOTIDASE III, MAGNESIUM ION, PHOSPHATE ION
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, M, Holmberg, B, Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
登録日2007-02-09
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition.
J.Biol.Chem., 282, 2007
2JCM
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Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with beryllium trifluoride
分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, MAGNESIUM ION, SULFATE ION, ...
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Loppnau, P, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-12-27
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2JBH
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Human phosphoribosyl transferase domain containing 1
分子名称: CALCIUM ION, GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ...
著者Welin, M, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Eklund, H, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
登録日2006-12-07
公開日2006-12-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Functional Studies of the Human Phosphoribosyltransferase Domain Containing Protein 1.
FEBS J., 277, 2010
2IC5
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Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-09-12
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
To be Published
1H2H
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Crystal structure of TM1643
分子名称: HYPOTHETICAL PROTEIN TM1643, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Yang, Z, Savchenko, A, Edwards, A, Arrowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2002-08-08
公開日2002-08-15
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
J. Biol. Chem., 278, 2003
2GSE
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Crystal Structure of Human Dihydropyrimidinease-like 2
分子名称: CALCIUM ION, Dihydropyrimidinase-related protein 2
著者Ogg, D, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Holmberg-Schiavone, L, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2006-04-26
公開日2006-05-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of human collapsin response mediator protein 2, a regulator of axonal growth.
J.Neurochem., 101, 2007
2I4I
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Crystal Structure of human DEAD-box RNA helicase DDX3X
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X
著者Hogbom, M, Karlberg, T, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2006-08-22
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
J.Mol.Biol., 372, 2007
1GTD
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NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG ID TT50) STRUCTURE OF MTH169, THE PURS SUBUNIT OF FGAM SYNTHETASE
分子名称: MTH169
著者Batra, R, Christendat, D, Saxild, H.H, Arrowsmith, C, Tong, L.
登録日2002-01-14
公開日2002-12-12
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Crystal Structure of Mth169, a Crucial Component of Phosphoribosylformylglycinamidine Synthetase
Proteins: Struct.,Funct., Genet., 49, 2002
2XIQ
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Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, MALONYL-COENZYME A, ...
著者Yue, W.W, Froese, D.S, Kochan, G, Chaikuad, A, Krojer, T, Muniz, J, Ugochukwu, E, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2010-06-30
公開日2010-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
2JGY
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The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)
分子名称: UMP SYNTHASE
著者Moche, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-02-16
公開日2007-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of Human Orotidine-5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps)
To be Published

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