2W2I

Crystal structure of the human 2-oxoglutarate oxygenase LOC390245

Summary for 2W2I

Entry DOI	10.2210/pdb2w2i/pdb
Descriptor	2-OXOGLUTARATE OXYGENASE, NICKEL (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase, chromosome 11
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus : B2RXH2
Total number of polymer chains	3
Total formula weight	124732.99
Authors	Yue, W.W.,Ng, S.,Shafqat, N.,Ugochukwu, E.,McDonough, M.,Pike, A.C.W.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Schofield, C.,Oppermann, U. (deposition date: 2008-10-31, release date: 2009-01-20, Last modification date: 2023-12-13)
Primary citation	Hillringhaus, L.,Yue, W.W.,Rose, N.R.,Ng, S.S.,Gileadi, C.,Loenarz, C.,Bello, S.H.,Bray, J.E.,Schofield, C.J.,Oppermann, U. Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family. J.Biol.Chem., 286:41616-, 2011 Cited by PubMed: 21914792 DOI: 10.1074/JBC.M111.283689 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation