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2IHB

Crystal structure of the heterodimeric complex of human RGS10 and activated Gi alpha 3

Summary for 2IHB
Entry DOI10.2210/pdb2ihb/pdb
DescriptorGuanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signalling 10, TETRAFLUOROALUMINATE ION, ... (6 entities in total)
Functional Keywordsg protein signalling, rgs, heterotrimeric g protein, signalling complex, structural genomics, structural genomics consortium, sgc, signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: P08754
Total number of polymer chains2
Total formula weight55793.21
Authors
Primary citationSoundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008
Cited by
PubMed: 18434541
DOI: 10.1073/pnas.0801508105
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.71 Å)
Structure validation

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