2IHB
Crystal structure of the heterodimeric complex of human RGS10 and activated Gi alpha 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(k) subunit alpha | polymer | 323 | 37201.3 | 1 | UniProt (P08754) Pfam (PF00503) | Homo sapiens (human) | Gi, alpha-3 |
| 2 | B (B) | Regulator of G-protein signalling 10 | polymer | 153 | 18021.4 | 1 | UniProt (Q96GN0) Pfam (PF00615) UniProt (by SIFTS) (O43665) | Homo sapiens (human) | |
| 3 | C (A) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
B: 2 - 152 (UniProt: Q96GN0)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55222.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 55793.2 |
