The TIR domain of human Toll-Like Receptor 10 (TLR10)

Summary for 2J67

DescriptorTOLL LIKE RECEPTOR 10 (2 entities in total)
Functional Keywordstir, il-1, toll, tlr10, membrane, receptor, inflammatory response, toll-like receptor 10, innate immunity, immune response, leucine-rich repeat, glycoprotein, transmembrane
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMembrane; Single-pass type I membrane protein (By similarity) Q9BXR5
Total number of polymer chains2
Total molecular weight42578.57
Primary citation
Nyman, T.,Stenmark, P.,Flodin, S.,Johansson, I.,Hammarstrom, M.,Nordlund, P.
The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283:11861-, 2008
PubMed: 18332149 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.C800001200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26771.1%5.1%12.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution