4RHW
| Crystal structure of Apaf-1 CARD and caspase-9 CARD complex | Descriptor: | Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ... | Authors: | Hu, Q, Wu, D, Yan, C, Shi, Y. | Deposit date: | 2014-10-03 | Release date: | 2014-10-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome. Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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5JNX
| The 6.6 A cryo-EM structure of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | Authors: | Gong, X, Qian, H.W, Zhou, X.H, Wu, J.P, Wan, T, Shi, Y, Gao, F, Zhou, Q, Yan, N. | Deposit date: | 2016-05-01 | Release date: | 2016-06-15 | Last modified: | 2020-08-05 | Method: | ELECTRON MICROSCOPY (6.56 Å) | Cite: | Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection Cell, 165, 2016
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4GNE
| Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | Descriptor: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | Authors: | Li, F, He, C, Wu, J, Shi, Y. | Deposit date: | 2012-08-17 | Release date: | 2013-01-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GND
| Crystal Structure of NSD3 tandem PHD5-C5HCH domains | Descriptor: | Histone-lysine N-methyltransferase NSD3, ZINC ION | Authors: | Li, F, He, C, Wu, J, Shi, Y. | Deposit date: | 2012-08-17 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GNF
| Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | Descriptor: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | Authors: | Li, F, He, C, Wu, J, Shi, Y. | Deposit date: | 2012-08-17 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GNG
| Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide | Descriptor: | GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ... | Authors: | Li, F, He, C, Wu, J, Shi, Y. | Deposit date: | 2012-08-17 | Release date: | 2013-01-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GXL
| The crystal structure of Galectin-8 C-CRD in complex with NDP52 | Descriptor: | GLYCEROL, Galectin-8, Peptide from Calcium-binding and coiled-coil domain-containing protein 2 | Authors: | Li, S, Wandel, M.P, Li, F, Liu, Z, He, C, Wu, J, Shi, Y, Randow, F. | Deposit date: | 2012-09-04 | Release date: | 2013-05-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.023 Å) | Cite: | Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy Sci.Signal., 6, 2013
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4IU9
| Crystal structure of a membrane transporter | Descriptor: | Nitrite extrusion protein 2 | Authors: | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | Deposit date: | 2013-01-20 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.005 Å) | Cite: | Structure and mechanism of a nitrate transporter. Cell Rep, 3, 2013
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4ITJ
| Crystal structure of RIP1 kinase in complex with necrostatin-4 | Descriptor: | IODIDE ION, N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | Deposit date: | 2013-01-18 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
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4ITI
| Crystal structure of RIP1 kinase in complex with necrostatin-3 analog | Descriptor: | 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | Deposit date: | 2013-01-18 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
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4IU8
| Crystal structure of a membrane transporter (selenomethionine derivative) | Descriptor: | NITRATE ION, Nitrite extrusion protein 2 | Authors: | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | Deposit date: | 2013-01-20 | Release date: | 2013-04-17 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structure and mechanism of a nitrate transporter. Cell Rep, 3, 2013
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4ITH
| Crystal structure of RIP1 kinase in complex with necrostatin-1 analog | Descriptor: | (5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1, ... | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | Deposit date: | 2013-01-18 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
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7WKK
| Cryo-EM structure of the IR subunit from X. laevis NPC | Descriptor: | Aaas-prov protein, IL4I1 protein, MGC83295 protein, ... | Authors: | Huang, G, Zhan, X, Shi, Y. | Deposit date: | 2022-01-10 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex. Cell Res., 32, 2022
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3KV5
| Structure of KIAA1718, human Jumonji demethylase, in complex with N-oxalylglycine | Descriptor: | FE (II) ION, JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, ... | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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3KV9
| Structure of KIAA1718 Jumonji domain | Descriptor: | FE (II) ION, JmjC domain-containing histone demethylation protein 1D, OXYGEN MOLECULE | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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3KVB
| Structure of KIAA1718 Jumonji domain in complex with N-oxalylglycine | Descriptor: | JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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3KVA
| Structure of KIAA1718 Jumonji domain in complex with alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ... | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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3L1L
| Structure of Arg-bound Escherichia coli AdiC | Descriptor: | ARGININE, Arginine/agmatine antiporter, nonyl beta-D-glucopyranoside | Authors: | Gao, X, Zhou, L, Shi, Y. | Deposit date: | 2009-12-13 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Mechanism of substrate recognition and transport by an amino acid antiporter Nature, 463, 2010
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3KV6
| Structure of KIAA1718, human Jumonji demethylase, in complex with alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ... | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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4KDO
| Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus in complex with human receptor analog LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-25 | Release date: | 2013-07-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut). Protein Cell, 4, 2013
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4KDM
| Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-25 | Release date: | 2013-07-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.496 Å) | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut). Protein Cell, 4, 2013
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4KDN
| Crystal structure of the hemagglutinin of ferret-transmissible H5N1 virus in complex with avian receptor analog LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-25 | Release date: | 2013-07-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.483 Å) | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut). Protein Cell, 4, 2013
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4KDQ
| Crystal structure of the hemagglutinin of A/Xinjiang/1/2006 virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Lu, X, Shi, Y, Zhang, W, Zhang, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-25 | Release date: | 2013-07-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Structure and receptor-binding properties of an airborne transmissible avian influenza A virus hemagglutinin H5 (VN1203mut). Protein Cell, 4, 2013
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4M75
| Crystal structure of Lsm1-7 complex | Descriptor: | CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-10-23 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4M77
| Crystal structure of Lsm2-8 complex, space group I212121 | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.111 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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