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PDB: 1963 件
1T2M
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BU of 1t2m by Molmil
Solution Structure Of The Pdz Domain Of AF-6
分子名称: AF-6 protein
著者Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y.
登録日2004-04-22
公開日2005-02-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J.Biol.Chem., 280, 2005
2IE4
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BU of 2ie4 by Molmil
Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid
分子名称: MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ...
著者Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
5FN2
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BU of 5fn2 by Molmil
Cryo-EM structure of gamma secretase in complex with a drug DAPT
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-04
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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BU of 5fn4 by Molmil
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FCG
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BU of 5fcg by Molmil
Crystal structure of Bcl-2 in complex with HBx-BH3 motif
分子名称: Apoptosis regulator Bcl-2, Protein X
著者Jiang, T.Y, Liu, M.H, Wu, J.P, Shi, Y.G.
登録日2015-12-15
公開日2016-02-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical analysis of Bcl-2 interaction with the hepatitis B virus protein HBx
Proc.Natl.Acad.Sci.USA, 2016
1K86
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BU of 1k86 by Molmil
Crystal structure of caspase-7
分子名称: caspase-7
著者Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y.
登録日2001-10-23
公開日2001-11-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
Cell(Cambridge,Mass.), 107, 2001
1K88
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BU of 1k88 by Molmil
Crystal structure of procaspase-7
分子名称: procaspase-7
著者Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y.
登録日2001-10-23
公開日2001-11-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
Cell(Cambridge,Mass.), 107, 2001
4M9R
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BU of 4m9r by Molmil
Crystal structure of CED-3
分子名称: Cell death protein 3
著者Xu, Y, Jeffrey, P.D, Shi, Y.G.
登録日2013-08-15
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.656 Å)
主引用文献Mechanistic insights into CED-4-mediated activation of CED-3
Genes Dev., 27, 2013
7TA8
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BU of 7ta8 by Molmil
NMR structure of crosslinked cyclophilin A
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M.
登録日2021-12-20
公開日2022-06-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink.
J.Am.Chem.Soc., 144, 2022
4N40
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BU of 4n40 by Molmil
Crystal structure of human Epithelial cell-transforming sequence 2 protein
分子名称: Protein ECT2
著者Zou, Y, Shao, Z.H, Li, F.D, Gong, D, Wang, C, Gong, Q, Shi, Y.
登録日2013-10-08
公開日2014-08-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4
Febs Lett., 588, 2014
1TMW
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BU of 1tmw by Molmil
Solution structure of Human Coactosin Like Protein D123N
分子名称: Coactosin-like protein
著者Dai, H, Wu, J, Xu, Y, Tang, Y, Ding, H, Shi, Y.
登録日2004-06-11
公開日2005-06-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Study on Solution Structure and Its binding function to F-actin
To be Published
4M38
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BU of 4m38 by Molmil
Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 complex with AdoHcy and histone H4 peptide
分子名称: Histone H4, Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE
著者Wang, C, Zhu, Y, Shi, Y.
登録日2013-08-06
公開日2014-04-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Structure, 22, 2014
3F4M
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BU of 3f4m by Molmil
Crystal structure of TIPE2
分子名称: CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2
著者Zhang, X, Wang, J, Shi, Y.
登録日2008-11-01
公開日2009-03-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
1K99
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BU of 1k99 by Molmil
Solution Structure of the first HMG box in human Upstream binding factor
分子名称: Upstream binding factor 1
著者Xu, Y, Yang, W, Wu, J, Shi, Y.
登録日2001-10-28
公開日2001-11-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first HMG box domain in human upstream binding factor.
Biochemistry, 41, 2002
8Y6P
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BU of 8y6p by Molmil
Structure of the auto-inhibited Dark monomer
分子名称: Apaf-1 related killer DARK
著者Tian, L, Li, Y, Shi, Y.
登録日2024-02-03
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Dark and Dronc activation in Drosophila melanogaster.
Proc.Natl.Acad.Sci.USA, 121, 2024
4M69
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BU of 4m69 by Molmil
Crystal structure of the mouse RIP3-MLKL complex
分子名称: CHLORIDE ION, MAGNESIUM ION, Mixed lineage kinase domain-like protein, ...
著者Xie, T, Peng, W, Yan, C, Wu, J, Shi, Y.
登録日2013-08-09
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Structural Insights into RIP3-Mediated Necroptotic Signaling
Cell Rep, 5, 2013
8X54
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BU of 8x54 by Molmil
Cryo-EM structure of human gamma-secretase in complex with APP-C99
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
登録日2023-11-16
公開日2024-05-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
8X52
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BU of 8x52 by Molmil
Cryo-EM structure of human gamma-secretase in complex with Abeta49
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
登録日2023-11-16
公開日2024-05-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
8X53
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BU of 8x53 by Molmil
Cryo-EM structure of human gamma-secretase in complex with Abeta46
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
登録日2023-11-16
公開日2024-05-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-02
公開日2024-03-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8Y7E
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BU of 8y7e by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
分子名称: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-04
公開日2024-03-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
7EVN
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BU of 7evn by Molmil
The cryo-EM structure of the DDX42-SF3b complex
分子名称: ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
7EP7
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BU of 7ep7 by Molmil
The complex structure of Gpsm2 and Whirlin
分子名称: G-protein-signaling modulator 2, Whirlin
著者Lin, L, Shi, Y, Wang, C, Zhu, J.
登録日2021-04-26
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Sci Adv, 8, 2022
1DU9
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SOLUTION STRUCTURE OF BMP02, A NATURAL SCORPION TOXIN WHICH BLOCKS APAMIN-SENSITIVE CALCIUM-ACTIVATED POTASSIUM CHANNELS, 25 STRUCTURES
分子名称: BMP02 NEUROTOXIN
著者Xu, Y, Wu, J, Pei, J, Shi, Y, Ji, Y, Tong, Q.
登録日2000-01-17
公開日2000-02-04
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of BmP02, a new potassium channel blocker from the venom of the Chinese scorpion Buthus martensi Karsch.
Biochemistry, 39, 2000

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