7XQ8

Structure of human B-cell antigen receptor of the IgM isotype

Summary for 7XQ8

Entry DOI	10.2210/pdb7xq8/pdb
EMDB information	33390
Descriptor	Chimera of Heavy chain of VRC01 antibody Fab and Isoform 2 of Immunoglobulin heavy constant mu, Light chain of Fab fragments of the VRC01 antibody,Immunoglobulin kappa constant, B-cell antigen receptor complex-associated protein alpha chain, ... (5 entities in total)
Functional Keywords	immunology, b cell signalling, adaptive immunity, antibody, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	250896.26
Authors	Chen, M.Y.,Su, Q.,Shi, Y.G. (deposition date: 2022-05-07, release date: 2022-08-17, Last modification date: 2022-08-31)
Primary citation	Su, Q.,Chen, M.,Shi, Y.,Zhang, X.,Huang, G.,Huang, B.,Liu, D.,Liu, Z.,Shi, Y. Cryo-EM structure of the human IgM B cell receptor. Science, 377:875-880, 2022 Cited by PubMed: 35981043 DOI: 10.1126/science.abo3923 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation