7XQ8
Structure of human B-cell antigen receptor of the IgM isotype
Summary for 7XQ8
Entry DOI | 10.2210/pdb7xq8/pdb |
EMDB information | 33390 |
Descriptor | Chimera of Heavy chain of VRC01 antibody Fab and Isoform 2 of Immunoglobulin heavy constant mu, Light chain of Fab fragments of the VRC01 antibody,Immunoglobulin kappa constant, B-cell antigen receptor complex-associated protein alpha chain, ... (5 entities in total) |
Functional Keywords | immunology, b cell signalling, adaptive immunity, antibody, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 250896.26 |
Authors | Chen, M.Y.,Su, Q.,Shi, Y.G. (deposition date: 2022-05-07, release date: 2022-08-17, Last modification date: 2022-08-31) |
Primary citation | Su, Q.,Chen, M.,Shi, Y.,Zhang, X.,Huang, G.,Huang, B.,Liu, D.,Liu, Z.,Shi, Y. Cryo-EM structure of the human IgM B cell receptor. Science, 377:875-880, 2022 Cited by PubMed: 35981043DOI: 10.1126/science.abo3923 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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