6MCZ
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6MD4
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![BU of 6md4 by Molmil](/molmil-images/mine/6md4) | |
6MD1
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![BU of 6md1 by Molmil](/molmil-images/mine/6md1) | |
6MD2
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6MD0
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6C1I
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![BU of 6c1i by Molmil](/molmil-images/mine/6c1i) | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 | Descriptor: | 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid | Authors: | Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J. | Deposit date: | 2018-01-04 | Release date: | 2018-12-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma. Nat Commun, 9, 2018
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6AUG
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6AVI
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6B7N
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![BU of 6b7n by Molmil](/molmil-images/mine/6b7n) | Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shang, J, Zheng, Y, Yang, Y, Liu, C, Geng, Q, Tai, W, Du, L, Zhou, Y, Zhang, W, Li, F. | Deposit date: | 2017-10-04 | Release date: | 2017-10-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-Electron Microscopy Structure of Porcine Deltacoronavirus Spike Protein in the Prefusion State J. Virol., 92, 2018
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7L5O
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![BU of 7l5o by Molmil](/molmil-images/mine/7l5o) | Crystal structure of the noncovalently bonded complex of rilzabrutinib with BTK | Descriptor: | (2E)-2-{(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Bradshaw, J.M, Brameld, K.A, Mrosek, M, Lammens, A, Blaesse, M. | Deposit date: | 2020-12-22 | Release date: | 2022-06-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | The Discovery Rilzabrutinib (PRN1008): A Reversible Covalent BTK Inhibitor for Immune Mediated Diseases To Be Published
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1U4R
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![BU of 1u4r by Molmil](/molmil-images/mine/1u4r) | Crystal Structure of human RANTES mutant 44-AANA-47 | Descriptor: | SULFATE ION, Small inducible cytokine A5 | Authors: | Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I. | Deposit date: | 2004-07-26 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors. Structure, 12, 2004
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1U4L
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![BU of 1u4l by Molmil](/molmil-images/mine/1u4l) | human RANTES complexed to heparin-derived disaccharide I-S | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETIC ACID, Small inducible cytokine A5 | Authors: | Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I. | Deposit date: | 2004-07-26 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors. Structure, 12, 2004
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1U4M
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![BU of 1u4m by Molmil](/molmil-images/mine/1u4m) | human RANTES complexed to heparin-derived disaccharide III-S | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose, ACETIC ACID, Small inducible cytokine A5 | Authors: | Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I. | Deposit date: | 2004-07-26 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors. Structure, 12, 2004
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1U4P
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![BU of 1u4p by Molmil](/molmil-images/mine/1u4p) | Crystal Structure of human RANTES mutant K45E | Descriptor: | ACETIC ACID, Small inducible cytokine A5 | Authors: | Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I. | Deposit date: | 2004-07-26 | Release date: | 2004-11-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors. Structure, 12, 2004
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5UGM
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![BU of 5ugm by Molmil](/molmil-images/mine/5ugm) | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Edaglitazone | Descriptor: | (5R)-5-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}methyl)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma, nonanoic acid | Authors: | Shang, J, Kojetin, D.J. | Deposit date: | 2017-01-09 | Release date: | 2018-01-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
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4OUH
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7JQG
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7SF6
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![BU of 7sf6 by Molmil](/molmil-images/mine/7sf6) | Crystal Structure of Siderophore Binding Protein FatB from Desulfitobacterium hafniense | Descriptor: | 1,2-ETHANEDIOL, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, CHLORIDE ION, ... | Authors: | Kim, Y, Patel, H.P, Nordquist, K.A, Schaab, K.M, Sha, J, Babnigg, G, Bond, A.H, Joachimiak, A, Midwest Center for Structural Genomics, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2021-10-03 | Release date: | 2021-12-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Crystal Structure of Siderophore Binding Protein FatB from Desulfitobacterium hafniense To Be Published
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7CPU
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![BU of 7cpu by Molmil](/molmil-images/mine/7cpu) | Cryo-EM structure of 80S ribosome from mouse kidney | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | Deposit date: | 2020-08-08 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
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7CPV
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![BU of 7cpv by Molmil](/molmil-images/mine/7cpv) | Cryo-EM structure of 80S ribosome from mouse testis | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | Deposit date: | 2020-08-08 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
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4UUD
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![BU of 4uud by Molmil](/molmil-images/mine/4uud) | Human dynamin 1 K44A superconstricted polymer stabilized with GTP | Descriptor: | DYNAMIN-1 | Authors: | Sundborger, A.C, Fang, S, Heymann, J.A, Ray, P, Chappie, J.S, Hinshaw, J.E. | Deposit date: | 2014-07-25 | Release date: | 2014-08-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | A Dynamin Mutant Defines a Superconstricted Prefission State. Cell Rep., 8, 2014
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2W05
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![BU of 2w05 by Molmil](/molmil-images/mine/2w05) | Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5b | Descriptor: | CELL DIVISION PROTEIN KINASE 2, N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE | Authors: | Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Breed, J, Byth, K.F, Culshaw, J.D, Finlay, M.R, Fisher, E, Green, C.P, Heaton, D.W, Nash, I.A, Newcombe, N.J, Oakes, S.E, Pauptit, R.A, Roberts, A, Stanway, J.J, Thomas, A.P, Tucker, J.A, Weir, H.M. | Deposit date: | 2008-08-08 | Release date: | 2008-10-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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4V00
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![BU of 4v00 by Molmil](/molmil-images/mine/4v00) | Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MONOTREME LACTATING PROTEIN | Authors: | Enjapoori, A.K, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | Deposit date: | 2014-09-10 | Release date: | 2015-09-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4V3J
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![BU of 4v3j by Molmil](/molmil-images/mine/4v3j) | Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN | Authors: | Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | Deposit date: | 2014-10-20 | Release date: | 2016-01-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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1JRL
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![BU of 1jrl by Molmil](/molmil-images/mine/1jrl) | Crystal structure of E. coli Lysophospholiase L1/Acyl-CoA Thioesterase I/Protease I L109P mutant | Descriptor: | Acyl-CoA Thioesterase I, IMIDAZOLE, SULFATE ION | Authors: | Lo, Y.-C, Lin, S.-C, Shaw, J.-F, Liaw, Y.-C. | Deposit date: | 2001-08-14 | Release date: | 2003-07-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of Escherichia coli Thioesterase I/Protease I/Lysophospholipase L1: Consensus Sequence Blocks Constitute the Catalytic Center of SGNH-hydrolases through a Conserved Hydrogen Bond Network J.Mol.Biol., 330, 2003
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